广西2014-2016年婴儿HIV感染早期诊断检测情况分析

发布时间：2018-11-25 15:44

【摘要】：目的了解2014-2016年广西婴儿艾滋病病毒(HIV)感染早期诊断检测情况。方法对2014-2016年间在广西婴儿HIV感染早期诊断区域实验室进行的广西婴儿早期诊断样本数据进行统计分析。结果 2014-2016年,广西婴儿早期诊断样本中,第1次送检样本为1 322份,在HIV暴露儿童出生后6周(42天)及以内采集的比例为32.68%(432/1 322),在HIV暴露儿童出生后2个月(60天)及以内采集的比例为87.07%(1 151/1 322),采集周期中位数45天;第2次送检样本为1 162份,在HIV暴露儿童出生后3个月(90天)及以内采集的比例为9.55%(111/1 162),在HIV暴露儿童出生后4个月(120天)及以内采集的比例为87.52%(1 017/1 162),采集周期中位数97天。两次早期诊断样本采集时点均滞后于国家方案的要求。两次检测结果均为阳性的样本为22份,阳性率为1.66%(22/1 322)。结论早期诊断样本量逐年增加,说明HIV病毒感染孕产妇数在增加,各级妇幼机构的随访能力在提高,但是样本采集时点滞后和时点范围差距大,要求区域实验室需完善项目管理和质控方面的工作,进一步提高我区HIV感染产妇及其所生婴儿的随访和管理工作。
[Abstract]:Objective to investigate the early diagnosis and detection of infant (HIV) infection in Guangxi from 2014-2016. Methods the sample data of early diagnosis of infant HIV infection in Guangxi from 2014 to 2016 were statistically analyzed. Results in 2014-2016, 1 322 samples were collected for early diagnosis of infants in Guangxi. The proportion of samples collected within 6 weeks (42 days) and within 6 weeks after HIV exposure was 32.68% (432 / 1 322). 87.07% (1 151 / 1 322) children were collected within 2 months (60 days) after HIV exposure, and the median sampling period was 45 days. 1 162 samples were collected at the second time. The percentage of children born 3 months (90 days) after HIV exposure was 9.55% (111 / 1 162). 87.52% (1 017 / 1 162) of children were collected within 4 months (120 days) after HIV exposure, and the median period was 97 days. Both early diagnostic samples were collected at a point that lagged behind the requirements of the national scheme. The positive rate was 1.66% (22 / 1 322). Conclusion the number of samples for early diagnosis is increasing year by year, which indicates that the number of pregnant women infected with HIV virus is increasing, and the follow-up ability of maternal and child institutions at all levels is improving, but the sampling time point is lagging behind and the time range is wide. The project management and quality control should be improved in order to improve the follow-up and management of HIV infected women and their babies.
【作者单位】：广西壮族自治区妇幼保健院;
【基金】：国家“十二五”计划“艾滋病和病毒性肝炎等重大传染病防治”科技重大专项课题——“母婴阻断失败后新生儿艾滋病毒清除治疗方案研究”(2015ZX10001001)~~
【分类号】：R725.1

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