3.0TMR动态增强联合扩散加权成像在子宫内膜癌术前评估中的价值

发布时间：2018-01-06 12:02

本文关键词：3.0TMR动态增强联合扩散加权成像在子宫内膜癌术前评估中的价值　出处：《南京医科大学学报(自然科学版)》2016年12期 　论文类型：期刊论文

【摘要】：目的 :探讨3.0TMR动态增强扫描(DCE-MRI)联合扩散加权成像(DWI)在评估诊断子宫内膜癌患者肌层浸润深度、宫颈侵犯和术前分期中的应用价值。方法:经病理证实的26例子宫内膜癌患者术前MRI影像资料,包括T_1WI、T_2WI、DCE-MRI和DWI序列,对照术后病理结果,评估应用DCE-MRI、DWI及DCE-MRI联合DWI法诊断子宫内膜癌肌层浸润、宫颈侵犯和术前分期的敏感性、特异性、准确率、阳性预测值、阴性预测值;比较不同成像方法对肌层浸润、宫颈侵犯和术前分期的准确率。结果:DCE-MRI、DWI及DCE-MRI联合DWI法判断肌层浸润深度的准确率分别为76.92%、73.08%和84.62%,DCE-MRI联合DWI法高于单独应用DCE-MRI和单独应用DWI法,差异具有统计学意义(P0.05);DCE-MRI、DWI及DCE-MRI联合DWI法判断宫颈侵犯的准确率分别为76.92%、73.08%和88.46%,DCE-MRI联合DWI法高于单独应用DCE-MRI和单独应用DWI法,差异具有统计学意义(P0.05);DCE-MRI、DWI及DCE-MRI联合DWI法判断分期的准确率分别为65.38%、53.85%和80.77%,DCEMRI联合DWI法高于单独应用DCE-MRI和单独应用DWI法,差异具有统计学意义(P0.05)。结论 :联合应用DCE-MRI和DWI较单独应用DCE-MRI或DWI可以更准确地进行子宫内膜癌术前评估,应常规应用于子宫内膜癌的术前检查。
[Abstract]:Objective: To investigate the dynamic enhanced 3.0TMR (DCE-MRI) combined with diffusion weighted imaging (DWI) in diagnosis of patients with endometrial carcinoma muscle layer infiltration depth, application value in staging and preoperative cervical invasion. Methods: 26 patients with pathologically confirmed endometrial cancer patients preoperative MRI image data, including T_1WI and T_2WI. DCE-MRI and DWI sequence, compared with postoperative pathological results, evaluate the application of DCE-MRI, DWI and DCE-MRI combined with DWI method for diagnosis of myometrial invasion of endometrial carcinoma, the sensitivity, the staging of cervical invasion and preoperative specificity, accuracy, positive predictive value, negative predictive value; comparison of different imaging methods on the infiltration of the muscle layer, accuracy the staging of cervical invasion and before surgery. Results: DCE-MRI, DWI and DCE-MRI combined with DWI method to determine the depth of myometrial invasion accuracy were 76.92%, 73.08% and 84.62%, DCE-MRI combined with DWI was significantly higher than that of DCE-MRI alone and DWI alone, the difference There was statistical significance (P0.05); DCE-MRI, DWI and DCE-MRI combined with DWI method to judge the accuracy of cervical invasion were 76.92%, 73.08% and 88.46%, DCE-MRI combined with DWI was significantly higher than that of DCE-MRI alone and DWI alone, the difference was statistically significant (P0.05); DCE-MRI, DWI and DCE-MRI combined with DWI method to determine the accuracy rate of staging were 65.38%, 53.85% and 80.77%, DCEMRI combined with DWI was significantly higher than that of DCE-MRI alone and DWI alone, the difference was statistically significant (P0.05). Conclusion: the combined application of DCE-MRI and DWI compared with the single application of DCE-MRI or DWI can evaluate the endometrial cancer to more accurately before, should check the routine application in endometrial carcinoma before the operation.

【作者单位】：徐州医科大学附属连云港医院影像科;
【分类号】：R445.2
【正文快照】： 子宫内膜癌是女性生殖系统常见的恶性肿瘤之一[1],其组织学类型、肿瘤病理分级,尤其是对子宫肌层浸润深度及宫颈侵犯情况与治疗方案的制定及患者的预后密切相关[2]。因此术前对子宫内膜癌进行准确评估意义重大。动态增强磁共振成像(dynamic contrast-enhanced MRI,DCE-MRI)和

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