扩散加权成像在预测肝细胞肝癌微血管浸润的价值

发布时间：2018-01-13 12:48

  本文关键词：扩散加权成像在预测肝细胞肝癌微血管浸润的价值　出处：《临床放射学杂志》2016年01期 　论文类型：期刊论文

  更多相关文章： 扩散加权成像 表观扩散系数 肝肿瘤 微血管浸润

【摘要】：目的评价扩散加权成像(DWI)对预测肝细胞肝癌微血管浸润的价值。方法搜集46例肝癌患者的DWI资料,测量肿瘤表观扩散系数(ADC)。比较微血管浸润阳性组和微血管浸润阴性组肝癌的ADC值,并进一步采用受试者工作特征曲线(ROC)分析ADC评价微血管浸润检测的诊断性能。结果 46例肝癌患者中24例微血管浸润阳性,22例微血管浸润阴性。微血管浸润阳性组的肝癌的ADC值低于微血管浸润阴性组,并具有统计学差异(1.22×10-3mm2/s,1.54×10-3mm2/s,P=0.0004)。应用ADC判断微血管浸润的曲线下面积(AUC)为0.78。以≤1.33×10-3mm2/s为界值判断肝癌存在微血管浸润的敏感性为75.0%,特异性为68.2%,阳性预测值为72.0%,阴性预测值为71.4%。结论 ADC值对于预测肝癌存在微血管浸润有潜在的价值。
[Abstract]:Objective to evaluate the value of diffusion-weighted imaging (DWI) in predicting microvascular infiltration in hepatocellular carcinoma (HCC). Methods DWI data of 46 patients with HCC were collected. To measure the apparent diffusion coefficient of tumor and compare the ADC value of HCC in the positive microvessel infiltrating group and the negative microvascular infiltrating group. ADC was used to evaluate the diagnostic performance of microvessel infiltration. Results 24 of 46 patients with liver cancer were positive for microvascular infiltration. The ADC value of 22 cases of HCC with positive microvessel infiltration was lower than that of negative microvessel infiltration group, and the difference was 1.22 脳 10 ~ (-3) mm ~ (-2) / s. 1.54 脳 10-3mm 2 / s. P0. 0004. The area under the curve of ADC for the determination of microvascular infiltration. The sensitivity of determining microvascular infiltration in HCC was 75.0%, taking 鈮，

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