孕妇产道20株B群链球菌耐药性分析

发布时间：2018-01-13 12:53

本文关键词：孕妇产道20株B群链球菌耐药性分析　出处：《现代预防医学》2016年05期 　论文类型：期刊论文

【摘要】：目的了解B群链球菌(Group B Streptococci,GBS)在晚孕期妇女产道内的定植率及耐药率,为国内孕妇产道B群链球菌常规筛查、预防治疗及抗生素的合理应用提供理论及数据支持。方法本研究共纳入275名晚孕期孕妇,取阴道和直肠棉拭子标本进行B群链球菌的分离、培养、鉴定和药物敏感实验,并对结果进行分析。结果 275例孕妇产道B群链球菌定植率7.27%。其中红霉素耐药率70.0%,克林霉素耐药率40.0%,四环素耐药率90.0%,左氧氟沙星耐药率40.0%,氯霉素耐药率30.0%,未分离出对青霉素、万古霉素和利奈唑胺耐药的菌株。结论临床医生对晚孕期妇女常规进行产道B群链球菌筛查,评估其对新生儿感染的影响,并选择合理的抗生素干预十分必要。
[Abstract]:Objective to investigate the colonization rate and drug resistance rate of Group B Streptococcus spp. GBSin late pregnant women in order to screen group B streptococcus in pregnant women in China. Methods 275 pregnant women in late pregnancy were collected from vaginal and rectum cotton swabs to isolate and culture group B streptococcus. Results the colonization rate of group B streptococcus in the birth canal of 275 pregnant women was 7.27. The resistance rate of erythromycin was 70.0%. The resistance rates of clindamycin, tetracycline, levofloxacin, chloramphenicol and chloramphenicol were 40.0, 90.0, 40.0 and 30.0, respectively. Conclusion it is necessary for clinicians to screen group B streptococcus in late pregnancy to evaluate the influence of vancomycin and linazolamide on neonatal infection and to select reasonable antibiotic intervention.
【作者单位】：四川大学华西第二医院检验科;四川大学华西第二医院产科;
【分类号】：R446.5;R714
【正文快照】： B群链球菌(Group B Streptococci,GBS)又名无乳链球菌(Streptococcus agalactiae)是一种革兰阳性的β溶血性链球菌,是导致成人及新生儿感染的重要的条件致病菌。近年来,B群链球菌已成为导致新生儿发生严重感染和死亡的主要病原菌之一。研究表明,母婴垂直传播是导致新生儿B群链

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