宫腔镜术后尿路感染的病原菌分布与抗菌药物应用研究

发布时间：2018-01-26 02:43

本文关键词： 宫腔镜手术尿路感染病原菌分布抗菌药物　出处：《中华医院感染学杂志》2016年02期 　论文类型：期刊论文

【摘要】：目的分析宫腔镜术后尿路感染的病原菌分布及抗菌药物应用,为更好的治疗尿路感染及使用抗菌药物提供理论依据。方法收集2013年4月-2015年4月医院就诊的974例宫腔镜术后尿路感染患者尿液标本,采集后及时送检,进行细菌鉴定及药敏试验,并对革兰阴性菌进行ESBLs检测。结果尿路感染患者共分离病原菌974株,其中革兰阳性菌242株占24.85%,革兰阴性菌590株占60.57%,真菌142例占14.58%;革兰阳性菌对13种抗菌药物存在不同程度的耐药性;大肠埃希菌的产ESBLs检出率为58.84%,肺炎克雷伯菌的产ESBLs检出率为39.68%;产ESBLs菌对抗菌药物的耐药性高于非产ESBLs菌。结论加强对宫腔镜术后尿路感染的病原菌分布及耐药性的研究,有利于推动宫腔镜手术及尿路感染治疗的发展。
[Abstract]:Objective to analyze the distribution of pathogenic bacteria and the application of antimicrobial agents in patients with urinary tract infection after hysteroscopy. Methods the urine samples of 974 patients with urinary tract infection after hysteroscopic surgery from April 2013 to April 2015 were collected. The bacteria identification and drug sensitivity test were carried out, and the gram-negative bacteria were detected by ESBLs. Results 974 strains of pathogenic bacteria were isolated from patients with urinary tract infection. Among them 242 Gram-positive bacteria accounted for 24.85, 590 Gram-negative bacteria accounted for 60.57 and 142 fungi accounted for 14.58; Gram-positive bacteria were resistant to 13 antimicrobial agents to varying degrees. The ESBLs production rate of Escherichia coli and Klebsiella pneumoniae was 58.84 and 39.68 respectively. The resistance of ESBLs producing bacteria to antimicrobial agents was higher than that of non ESBLs producing bacteria. Conclusion the study on the distribution and drug resistance of urinary tract infections after hysteroscopy is strengthened. It is helpful to promote the development of hysteroscopic surgery and the treatment of urinary tract infection.
【作者单位】：郑州大学第一附属医院妇科;
【基金】：河南省自然科学基金资助项目(0611044800)
【分类号】：R446.5
【正文快照】： 尿路感染是仅次于呼吸系统感染的医院感染之一,患者机体免疫力下降或患者的泌尿系统受到器械操作时损伤黏膜,病原菌侵袭泌尿系统,引起尿路感染[1-2]。本研究收集2013年4月-2015年4月来医院就诊的974例宫腔镜手术术后尿路感染患者的尿液标本,研究尿路感染的病原菌分布及其耐药

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