某医院患者金黄色葡萄球菌感染的临床分布及耐药性分析

发布时间：2018-02-26 21:40

本文关键词： 金黄色葡萄球菌医院感染耐药性　出处：《中国消毒学杂志》2016年09期 　论文类型：期刊论文

【摘要】：目的了解医院住院患者金黄色葡萄球菌感染分布特征及耐药性,为临床选择抗菌药物防控其感染提供依据。方法采用病原菌分离鉴定和药敏试验方法,对某医院临床送检病原学标本进行检测并对结果进行统计分析。结果从该医院住院患者送检病原学标本中共检出金黄色葡萄球菌201株,其中有46.7%分离自痰液、有20.0%分离自脓液,分离自分泌物标本占17.4%。临床分离的金黄色葡萄球菌对万古霉素、替考拉宁和利奈唑胺等抗菌药物全部敏感;对其他临床常用抗菌药物呈现出不同耐药性;耐甲氧西林金黄色葡萄球菌(MRSA)对庆大霉素、氨苄西林和头孢唑林等抗菌药物的耐药率明显高于甲氧西林敏感菌株。结论该医院临床分离的金黄色葡萄球菌主要分离自痰液、脓液和分泌物,耐药性严重,提示应加强药敏试验,并以此指导临床选择抗菌药物。
[Abstract]:Objective to investigate the distribution characteristics and drug resistance of Staphylococcus aureus infection in hospitalized patients, and to provide the basis for clinical selection of antimicrobial agents to prevent and control their infection. Results A total of 201 strains of Staphylococcus aureus were detected from the pathogenic specimens of hospitalized patients in a hospital, of which 46.7% strains were isolated from sputum and 20.0% strains from pus. The clinical isolates of Staphylococcus aureus were all sensitive to vancomycin, teicoplanin and linazolamide, and showed different drug resistance to other commonly used antibiotics. The resistant rate of MRSAs to gentamicin, ampicillin and cefazolin was significantly higher than that of methicillin-sensitive strains. Conclusion Staphylococcus aureus isolated clinically in this hospital was mainly isolated from sputum. The drug resistance of pus and secretions is serious, which suggests that antimicrobial susceptibility test should be strengthened to guide clinical selection of antimicrobial agents.
【作者单位】：湖北省疾病预防控制中心;重庆医科大学公共卫生与管理学院;
【分类号】：R446.5

【相似文献】