倒班相关睡眠障碍与倒班耐受性

发布时间：2018-03-09 06:44

本文选题：倒班　切入点：睡眠　出处：《中国临床心理学杂志》2016年06期 　论文类型：期刊论文

【摘要】：长期倒班易引起生物节律紊乱,导致倒班相关睡眠障碍(SWSD)与其他心身问题。而倒班耐受性存在个体差异,受到节律类型、人格特质、社会支持等心理社会因素影响。同时,节律调节涉及体内激素、神经生化、节律基因表达等的作用,因此SWSD与倒班耐受的个体差异也有生物及遗传基础。目前针对我国倒班人群的研究相当有限。未来可采取前瞻性队列研究和病例对照研究设计,借助流行病学调查、表观遗传分析、神经影像、神经化学波谱定量等方法技术手段,研究我国SWSD的流行病学特征和变化转归轨迹,探索SWSD的心理社会层面影响因素以及可能的遗传易感性与神经生化层面的内表型,并在此基础上甄别倒班耐受的预测指标,开发有助提升倒班耐受、降低SWSD风险的干预方案。
[Abstract]:Long-term shift shift may lead to disorder of biological rhythm, which leads to shift related sleep disorder (SWSD) and other psychosomatic problems. However, shift tolerance is affected by psychological and social factors, such as rhythm type, personality trait, social support, etc. At the same time, there are individual differences in shift tolerance, such as rhythm type, personality trait, social support and so on. Rhythmic regulation involves the effects of hormones, neurobiochemistry, rhythmic gene expression, etc. Therefore, the individual differences between SWSD and shift tolerance also have biological and genetic basis. At present, the study of shift shift population in China is very limited. In the future, prospective cohort study and case-control study design can be adopted, with the help of epidemiological investigation. Epigenetic analysis, neuroimaging, neurochemical spectrum quantification and other methods were used to study the epidemiological characteristics and change track of SWSD in China. To explore the influence factors of psychosomatic level, the possible genetic susceptibility and the endogenous phenotype of SWSD, and on this basis to identify the predictive indicators of shift tolerance, and to develop an intervention scheme which can help to enhance shift tolerance and reduce the risk of SWSD.
【作者单位】：华南师范大学心理学院/华南师范大学心理应用研究中心;
【基金】：国家自然科学基金项目(31671165) 中国博士后科学基金第9批特别资助项目(2016T90790) 广东省委宣传部打造“理论粤军”2014年度重点课题(WT1424)
【分类号】：R740

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