184例急性髓系白血病患者DA方案首次化疗后血小板输注调查

发布时间：2018-03-22 19:50

本文选题：白血病　切入点：血小板输注　出处：《中国输血杂志》2016年12期 　论文类型：期刊论文

【摘要】：目的调查急性髓系白血病患者DA方案首次化疗后临床血小板输注情况及输血不良反应的发生率。方法收集病例的输血记录、输血科发血记录、患者住院病历输血不良反应记录、输血种类及输血量等,利用SPSS对相关数据进行分析处理。结果 184例患者共输注血小板668次;输注前血小板为(11.8±10.0)×109/L,输注后血小板(24.4±23.9)×109/L,患者血小板输注后较输注前计数显著上升(Z=15.975,P0.05)。有26例出现不同程度出血,出血发生率为14.1%。血小板申请平均等待时间为1.5 d,严重出血病例没有发现因血小板输注延误造成。共出现24次输血不良反应,发生率为3.6%,其中发热非溶血性输血反应10例,过敏反应14例。结论血小板输注是急性髓系白血病化疗患者重要的支持治疗,应严格掌握输注指征,综合评价患者出血状况等临床因素,从而提高输注有效率,减少输血不良反应。
[Abstract]:Objective to investigate the clinical platelet transfusion and the incidence of adverse reactions after DA regimen in patients with acute myeloid leukemia. The data were analyzed by SPSS. Results there were 668 platelet transfusions in 184 patients. The platelet count was 11.8 卤10.0 脳 10 9 / L before infusion and 24.4 卤23.9 脳 10 9 / L after infusion. The incidence of hemorrhage was 14.1.The average waiting time for platelet application was 1.5 days. No delay in platelet transfusion was found in severe bleeding cases. There were 24 adverse reactions of blood transfusion, the incidence rate was 3.6, among which 10 cases were febrile non-hemolytic transfusion reaction. Conclusion Platelet infusion is an important supportive therapy for patients with acute myeloid leukemia. The indication of transfusion should be strictly grasped and clinical factors such as bleeding status should be comprehensively evaluated in order to improve the effective rate of infusion. To reduce the adverse reaction of blood transfusion.
【作者单位】：四川大学华西医院输血科;
【分类号】：R733.71;R457.1

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