中心静脉集束化干预策略预防导管相关性血流感染的Meta分析

发布时间：2018-03-30 13:03

本文选题：中心静脉导管　切入点：导管相关性血流感染　出处：《护理学报》2016年08期

【摘要】：目的采用Meta分析方法系统评估中心静脉集束化干预策略预防导管相关性血流感染的效果。方法计算机检索中国学术期刊全文数据库(CNKI)、中文科技期刊全文数据库(VIP)、万方数据库、维普数据库、PubMed、MEDLINE、EMBASE、Cochrane Library中英文数据库,检索关于中心静脉集束化干预策略预防导管相关性血流感染的相关研究,按照纳入与排除标准筛选文献、提取资料并评价纳入研究的质量后采用Revman和Stata软件进行Meta分析,计算合并OR值及其95%CI,并进行发表偏倚评估及敏感性分析。结果共11项研究纳入,包括7 531例中心静脉置管患者。Meta分析结果表明,中心静脉集束化干预策略组较常规护理组显著降低ICU患者导管相关性血流感染发生率[OR=0.40,95%CI(0.31,0.50),P0.01]和导管病原菌数[OR=0.39,95%CI(0.29,0.53),P0.01]。结论中心静脉集束化干预策略预防导管相关性血流感染有效,建议临床推广使用。
[Abstract]:Objective to evaluate the effectiveness of central venous cluster intervention strategy in preventing catheter-related blood flow infection by using Meta analysis method. Methods the full text database of Chinese academic journals (CNKI), the full text database of Chinese scientific and technological periodicals (CSTC) and the Wanfang database were searched by computer. The WebMed database: MEDLINE EMBASEN Cochrane Library Chinese and English database was used to search for the relevant studies on the intervention strategy of central venous cluster to prevent catheter-related blood flow infection, and to screen the literature according to the inclusion and exclusion criteria. After extracting the data and evaluating the quality of the study, Meta analysis was carried out with Revman and Stata software, the combined OR value and 95% CI were calculated, and the publication bias assessment and sensitivity analysis were carried out. Meta-analysis, including 7,531 patients with central venous catheterization, showed that. The incidence of catheter-related blood flow infection in patients with ICU was significantly lower in the central venous cluster intervention group than in the routine nursing group [ORO 0.4095 CI 0.31 + 0.50 P0.01] and the number of pathogenic bacteria in the catheter [ORO 0.39995 CI 0.290.53]. Conclusion the central venous cluster intervention strategy is effective in the prevention of catheter-related blood flow infection. It is suggested that clinical application be popularized.
【作者单位】：湖北医药学院附属人民医院护理部;湖北医药学院附属人民医院公共卫生与医院感染管理处;湖北医药学院附属人民医院神经内科;
【基金】：湖北省教育厅人文社会科学基金项目(15G100)
【分类号】：R473.5

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