糖尿病肾病合并足感染的病原菌分布及药敏性观察

发布时间：2018-04-05 08:04

本文选题：糖尿病肾病　切入点：足感染　出处：《中华医院感染学杂志》2016年24期

【摘要】：目的了解糖尿病肾病合并足感染的病原菌分布及药敏性,为该疾病的临床诊断和合理用药提供研究依据。方法选择2013年1月-2015年12月收治的糖尿病肾病合并足感染患者115例,采集足部浅表创面与深部脓腔标本,鉴定标本中的菌株种类,并对主要病原菌进行药敏试验。结果 115例患者共取得143份有效标本,分离出175株病原菌,以革兰阳性菌为主,占57.86%;39株金黄色葡萄球菌中检测出MRSA菌株14株,MRSA阳性率为35.90%;28株大肠埃希菌中检测出产ESBLs菌株8株,产ESBLs菌阳性率为28.57%;金黄色葡萄球菌、粪肠球菌对利奈唑胺、万古霉素的敏感率均为100.00%。结论通过监测病原菌的分布、变化及其药敏特点,可确立合理的抗菌药物应用方案,有利于糖尿病肾病合并足感染的治疗。
[Abstract]:Objective to investigate the distribution of pathogenic bacteria and drug sensitivity of diabetic nephropathy complicated with foot infection, and to provide the basis for clinical diagnosis and rational drug use of diabetic nephropathy.Methods 115 cases of diabetic nephropathy complicated with foot infection were selected from January 2013 to December 2015. The superficial wound and deep pus cavity of foot were collected and the strains were identified and the main pathogens were tested for drug sensitivity.Results A total of 143 effective specimens were obtained from 115 patients and 175 strains of pathogenic bacteria were isolated. Gram-positive bacteria were the main pathogens, and 14 strains of MRSA strains were detected in 39 strains of Staphylococcus aureus. The positive rate of MRSA strains was 35.900.28 strains of Escherichia coli were detected, and 8 strains of ESBLs producing strains were detected.The positive rate of ESBLs producing bacteria was 28.57.The sensitivity of Staphylococcus aureus and Enterococcus faecalis to linazolamine and vancomycin were all 100.005.Conclusion by monitoring the distribution, changes and drug sensitivity of pathogenic bacteria, a reasonable application scheme of antimicrobial agents can be established, which is beneficial to the treatment of diabetic nephropathy with foot infection.
【作者单位】：丽水市人民医院检验科;
【基金】：2013年浙江省医药卫生一般研究计划(2013KYB278)
【分类号】：R587.2;R692.9;R446.5

【相似文献】