序贯器官衰竭估计评分预测严重感染预后的临床研究

发布时间：2018-04-16 09:34

本文选题：序贯器官衰竭 + 预测　；参考：《中华医院感染学杂志》2016年10期

【摘要】：目的探讨序贯器官衰竭估计(SOFA)评分对急诊严重感染患者预后的影响,为预测急诊严重感染患者预后提供理论指导。方法选取2013年2月-2015年2月于医院接受治疗的184例急诊严重感染患者作为研究对象,根据结局将患者分为两组,142例生存患者为观察组,42例死亡患者为对照组,两组患者均采用同样的抗感染治疗方式,计算两组患者在在入院72h后的各个阶段的SOFA评分,对比患者SOFA评分和病死率,对比两组患者入院前后的SOFA评分,对比两组患者身体器官和整体的SOFA评分情况;采用SPSS16.0软件对数据进行统计分析。结果 184例急诊严重感染患者在入院72h后的各个阶段SOFA评分和患者病死率之间存在关联,SOFA评分4时,患者病死率为0;SOFA评分为4~8分时,患者病死率为7.14%;SOFA评分为9~13分时,患者病死率为13.64%;SOFA评分为14~16分时,患者病死率为20.59%;SOFA评分16分时,患者病死率为100.00%,差异有统计学意义(P0.05);观察组患者T0SOFA评分(入院时的评分)和T72SOFA评分(入院72h后的评分)明显低于对照组,两组比较差异有统计学意义(P0.05);观察组患者损伤的器官个数评分为(2.9±1.2)分,对照组为(4.6±2.1)分,对照组高于观察组,对照组六大功能器官的评分也明显高于观察组的评分,两组差异有统计学意义(P0.05)。结论 SOFA评分能很好的预测急诊严重感染患者的预后,值得在临床推广应用。
[Abstract]:Objective to investigate the influence of SOFA-score on prognosis of patients with severe infection in emergency department, and to provide theoretical guidance for predicting prognosis of patients with severe infection in emergency department.Methods 184 emergency patients with severe infection were selected from February 2013 to February 2015. According to the outcome, the patients were divided into two groups: 142 survival patients as the control group, 42 dead patients as the control group.The patients in both groups were treated with the same anti-infective therapy. The SOFA scores, the SOFA scores, the mortality rate and the SOFA scores before and after admission were calculated in each stage of the two groups at 72 h after admission.The SOFA scores of the two groups were compared, and the data were statistically analyzed by SPSS16.0 software.Results there was a correlation between the SOFA score and the fatality rate in all stages of emergency severe infection patients 72 hours after admission. When the fatality rate was 4, the mortality rate was 4 ~ 8, and the mortality rate was 7. 14 and 9 ~ 13, respectively.The fatality rate of patients was 13.64 when the score of sofa was 14 ~ 16, and the mortality of patients was 20.59 when the score of sofa was 16.The mortality rate of the patients was 100.000.The difference was statistically significant (P 0.05), the scores of T0SOFA (at admission) and T72SOFA (at 72 hours after admission) in the observation group were significantly lower than those in the control group.There was significant difference between the two groups (P 0.05), the score of the number of injured organs in the observation group was 2.9 卤1.2), the score in the control group was 4.6 卤2.1), the score in the control group was higher than that in the observation group, and the score of the six major functional organs in the control group was significantly higher than that in the observation group.The difference between the two groups was statistically significant (P 0.05).Conclusion SOFA score can predict the prognosis of patients with severe infection in emergency department, and it is worth popularizing in clinic.
【作者单位】：宁波大学医学院附属医院急诊内科;宁波国际旅行卫生保健中心;
【基金】：浙江省卫生厅基金资助项目(ZW-2010B030)
【分类号】：R459.7

【相似文献】