登革热患者血小板输注的临床评价

发布时间：2018-04-19 07:51

  本文选题：登革热 + 伴慢性病　； 参考：《中国输血杂志》2016年03期

【摘要】：目的分析登革热(DF)患者血小板输注有效性及合理性。方法回顾性分析本院2014年住院的805名登革热患者的临床资料及相关检验室数据,根据患者伴慢性病情况分为DF伴心脑血管疾病组(n=475)、DF伴其他慢性疾病组(n=229)和DF无伴慢性疾病组(n=101);按照患者极期Plt(×10~9/L)最低值情况分为最低100组(n=78),最低50-100组(n=375)和最低50组(n=352);依据患者是否输注血小板,分为输注组(n=81)和非输注组(n=271),将输注血小板患者按其输注前的Plt(×10~9/L)P$,分20组(n=58)和≥20组(n=23)。依据各组患者输注血小板前后的Plt、对患者血小板输注指征、病程及输注血小板情况做统计分析。结果 1)极期不同Plt(×10~9/L)最低值患者病程100组与50-100组为:7.1±1.2 vs 8.5±1.9(P0.05),50组为13.8±6.1(P0.05)。2)输注组和非输注2组DF患者Plt从极期最低值回升至100的恢复时间(d)分别为:5.2±1.1 vs 5.1±3.2(P0.05);病程(d)分别为:9.2±4.3 vs 8.9±4.5(P0.05)。3)极期DF患者Plt(×10~9/L)平均输注量(U)20组和≥20组分别为1.2±0.3 vs 2.1±0.2(P0.05);出血率分别为5.2%(3/58)vs 4.3%(1/23)(P0.05);输血反应过敏反应、发热率分别为6.9%(4/58)vs 10.3%(6/58)vs 13.0%(3/23)17.4%(4/23)(P0.05);输注无效发生率为5.2%(3/58)vs 4.3%(1/23)(P0.05)。结论 DF患者血小板减少的程度与感染的严重程度相关,输注血小板对患者血小板恢复和病程无影响。
[Abstract]:Objective to analyze the validity and rationality of platelet transfusion in patients with DFD.Methods the clinical data and relevant laboratory data of 805 patients with dengue fever hospitalized in our hospital in 2014 were analyzed retrospectively.According to the condition of chronic diseases, DF patients with cardiovascular and cerebrovascular diseases were divided into two groups: DF with cardio-cerebrovascular diseases (DF) and other chronic diseases (n = 229) and DF without chronic diseases (n = 101). According to the minimum value of Plt (脳 10 ~ (9 / L)), divided into the lowest 100 groups (n ~ (78), 50 ~ 100 n ~ (37 5)) and the lowest 50 groups (n = 50).According to whether the patient is infused with platelets,The patients with platelet transfusion were divided into two groups according to Plt (脳 10 ~ 9 / L ~ (-1)) and 鈮，

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