HIFU消融不同T2WI信号子宫肌瘤疗效差异的组织声学性质

发布时间：2018-04-27 07:05

本文选题：子宫肌瘤 + 高强度聚焦超声消融　；参考：《中国介入影像与治疗学》2016年07期

【摘要】：目的探讨HIFU消融T2WI低、等、高信号子宫肌瘤组织声衰减和声速的差异。方法收集经手术切除的子宫肌瘤标本45个。对患者术前行MR检查,根据T2WI信号强度将肌瘤分为低信号、等信号、高信号3种类型。采用插入取代式脉冲传输法测量肌瘤标本的声速和声衰减。结果 45个子宫肌瘤标本中,T2WI低信号肌瘤7个,等信号肌瘤9个,高信号肌瘤29个,其组织声速分别为(1 597.86±15.17)m/s、(1 586.70±10.83)m/s、(1 576.57±10.06)m/s,低、等信号肌瘤组织与高信号肌瘤组织比较差异均有统计学意义(P均0.05);声衰减分别为(4.03±1.34)dB/cm、(2.54±1.17)dB/cm、(1.04±0.66)dB/cm,低和等信号肌瘤组织与高信号肌瘤组织、低信号肌瘤组织与等信号肌瘤组织比较差异均有统计学意义(P均0.05)。结论 T2WI低、等、高信号子宫肌瘤组织声速、声衰减的差异可能是导致HIFU消融子宫肌瘤疗效差异的重要原因。
[Abstract]:Objective to investigate the difference of sound attenuation and sound velocity in hysteromyoma tissue with HIFU ablation of T2WI. Methods 45 uterine myoma specimens were collected. Mr examination was performed before operation. According to the intensity of T2WI signal, myoma was classified into three types: low signal, equal signal and high signal. The sound velocity and sound attenuation of myoma specimens were measured by insertion substitution pulse transmission method. Results in 45 uterine leiomyoma specimens, there were 7 hypointential leiomyomas on T2WI, 9 isointense leiomyomas and 29 hyperintense leiomyomas. The sound velocities of their tissues were 1 597.86 卤15.17 m / s, 1 586.70 卤10.83 渭 m / s and 1 576.57 卤10.06 渭 m / s, respectively. There were significant differences between iso-signal leiomyoma tissue and hyperintense leiomyoma tissue (P < 0.05), sound attenuation were 4.03 卤1.34 dB / cm ~ (-1) and 2.54 卤1.17 ~ (?) dB / cm ~ (-1) ~ 1.04 卤0.66 ~ (dB) 路cm ~ (-1) respectively, hypochromatic leiomyoma tissue and high signal leiomyoma tissue. There were significant differences between hypointential leiomyoma tissue and iso-signal leiomyoma tissue (P < 0.05). Conclusion the difference of sound velocity and attenuation in hysteromyoma tissues with low, equal and high signal T2WI may be an important reason for the difference in the effect of HIFU ablation on uterine leiomyoma.
【作者单位】：重庆医科大学生物医学工程学院省部共建超声医学工程国家重点实验室超声医学工程重庆市重点实验室;
【基金】：国家自然科学基金(11574039、11274404) 国家重点基础研究发展计划(973计划)项目(2011CB707900、2012CB722402)
【分类号】：R445.2;R737.33

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