改进皮肤与瓶盖消毒方法对血培养凝固酶阴性葡萄球菌检出率的影响

发布时间：2018-05-17 12:32

本文选题：新生儿 + 血培养　；参考：《中国感染控制杂志》2016年05期

【摘要】：目的比较不同的皮肤及瓶盖消毒方法对凝固酶阴性葡萄球菌(CNS)检出率的影响,为临床改进采集流程及提高血培养检测准确性提供依据。方法选取某院新生儿科2012年6月—2014年8月送检的血培养标本,2012年6月—2013年6月血培养标本为对照组(常规消毒采集流程),2013年8月—2014年8月血培养标本为干预组(改进皮肤及瓶盖消毒方法),比较两组标本CNS检出率。结果对照组543份血培养标本检出病原菌41株,阳性率7.55%;干预组853份血培养标本检出病原菌21株,阳性率2.46%。对照组CNS检出率为4.97%(27株),其中耐甲氧西林凝固酶阴性葡萄球菌(MRCNS)12株,检出率为2.21%;干预组CNS检出率为0.82%(7株),其中MRCNS 6株,检出率为0.70%。两组患者CNS及MRCNS的检出率比较,差异均有统计学意义(χ2分别为24.07、5.92,均P0.05)。结论改进采集血培养标本时皮肤及瓶盖消毒方法,能降低CNS检出率。
[Abstract]:Objective to compare the effect of different skin and bottle cap disinfection methods on the detection rate of coagulase negative staphylococcus (CNS) and to provide evidence for improving the collection process and improving the accuracy of blood culture detection. Methods Blood culture samples were collected from a hospital from June 2012 to August 2014. The blood culture samples from June 2012 to June 2013 were selected as the control group (routine disinfection and collection process, August 2013-August 2014). The blood culture samples were dried from August 2013 to August 2014. The detection rate of CNS was compared between the two groups. Results 41 strains of pathogenic bacteria were detected in 543 samples of blood culture in control group and 21 strains were detected in 853 samples of blood culture in intervention group with a positive rate of 2.46%. The detection rate of CNS in the control group was 4.97 / 27, among which 12 strains were methicillin-resistant coagulase-negative staphylococci, the positive rate was 2.21, while in the intervention group, the detection rate of CNS was 0.82and 7 strains, of which 6 strains were MRCNS (0.70%). The positive rates of CNS and MRCNS were significantly different between the two groups (蠂 ~ 2 = 24.07 卤5.92, P < 0.05). Conclusion the improved disinfection method of skin and bottle cap can reduce the detection rate of CNS.
【作者单位】：湖北省荆门市康复医院;
【分类号】：R446.5

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