脉搏波波速法无创血压测量中多模量血压计算模型研究

发布时间：2018-05-17 12:44

本文选题：脉搏波波速法 + 无创血压测量　；参考：《中国生物医学工程学报》2016年06期

【摘要】：针对脉搏波波速法无创血压测量中血压计算模型建模困难和模型计算精度较低的问题,结合TPTT、ln(TPTT)及(1/TPTT)2等模量建立多模量血压计算模型。首先,利用99名随机测试者的实验数据确定多模量模型参数,并基于实验数据计算各模型性能评价指标,其中多模量血压计算模型拟合相关系数最大,为0.891,误差方差最小,仅为6.1,实验表明,多模量血压计算模型具有更好的拟合效果和更低的计算误差。然后,利用医用水银血压计和自主设计的多模量血压测量系统两种方法采集另外36名随机测试者的收缩压和舒张压数据,并计算两种方法采集数据间的相关参数,其中收缩压差值的绝对值d6 mm Hg,差值均值E_d=0.55 mm Hg,差值的标准差δ_d=2.98 mm Hg;舒张压差值的绝对值d6 mm Hg,差值均值E_d=0.57 mm Hg,差值的标准差δ_d=3.42 mm Hg,完全符合美国医疗仪器促进协会SP10-199中对电子血压计测量差值8 mm Hg的要求。最后,采用Bland-Altman差值法,对两种方法测量数据一致性进行检验,发现舒张压与收缩压的95%一致性界限分别为(-5.3,6.4)和(7.2,-6.2),完全在临床血压测量可接受范围之内,较好地证明多模量血压计算模型用于无创血压测量的有效性。研究结果表明,多模量血压计算模型可以应用于脉搏波波速法无创血压测量。
[Abstract]:In view of the difficulty of modeling the blood pressure model and the low accuracy of the model in pulse wave velocity noninvasive blood pressure measurement, a multimode blood pressure calculation model was established by combining TPTT / TPTT and TPTT / TPTT / TPTT / TPTT / TPTT / TPTT / TPTT / TPTT / TPTT / TPTT / TPTT. First of all, the parameters of multiple modulus model are determined by using the experimental data of 99 random subjects, and the performance evaluation indexes of each model are calculated based on the experimental data. The fitting correlation coefficient of the multimodule blood pressure calculation model is the largest, which is 0.891and the error variance is the smallest. The experimental results show that the multimode blood pressure calculation model has better fitting effect and lower calculation error. Then, the systolic and diastolic blood pressure data of 36 random subjects were collected by using the medical mercury sphygmomanometer and the self-designed multimode blood pressure measurement system, and the relevant parameters between the two methods were calculated. The absolute value of systolic pressure difference is d6 mm Hg, the mean value of difference is E_d=0.55 mm Hg, the standard deviation of difference is 未 D / D = 2.98 mm Hg, the absolute value of diastolic pressure difference is d 6 mm Hg, the mean value of difference is E_d=0.57 mm Hg, and the standard deviation 未 D / D of difference is 3.42 mm Hg, which is fully in line with the promotion of American medical instruments. Association SP10-199 requirements for electronic sphygmomanometer measurement difference of 8 mm Hg. Finally, the Bland-Altman difference method was used to test the data consistency of the two methods. The 95% consistency limits of diastolic blood pressure and systolic blood pressure were found to be -5.3f6.4and 7.2mg-6.2respectively, which were completely within the acceptable range of clinical blood pressure measurement. The validity of multimode blood pressure calculation model in non-invasive blood pressure measurement is well proved. The results show that the multimode blood pressure calculation model can be applied to pulse wave velocity noninvasive blood pressure measurement.
【作者单位】：西南石油大学机电工程学院;重庆市肿瘤医院手术室;
【基金】：西南石油大学研究生创新基金(CXJJ2015022)
【分类号】：R443.5

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