郑州地区儿童血清神经元特异性烯醇化酶参考区间的建立

发布时间：2018-05-25 15:45

本文选题：神经元特异性烯醇化酶 + 参考值　；参考：《重庆医学》2016年31期

【摘要】：目的建立郑州地区0~14岁健康儿童血清神经元特异性烯醇化酶(NSE)的参考区间。方法检测1 001名0~14岁健康儿童血清NSE。将研究对象按性别和年龄分组(1个月组、1个月至3岁组、3岁组),对各项参数进行统计学分析,得出各年龄组儿童血清NSE的参考区间。结果 0~14岁儿童不同性别间血清NSE水平差异无统计学意义(P0.05);不同年龄组间血清NSE水平差异有统计学意义(P0.05)。3个年龄组的参考区间分别是0~32.13mg/L(1月组),0~23.26mg/L(1个月至3岁组)和0~21.47mg/L(3岁组)。结论儿童各年龄组的NSE参考区间具有明显差异。建立不同年龄段的NSE参考区间,对于临床疾病的诊断和评估具有重要意义。
[Abstract]:Objective to establish a reference range for serum neuron specific enolase (NSE) of 14 year old healthy children in Zhengzhou area. Methods Serum NSE was detected in 1 001 healthy children aged 0 ~ 14 years. The subjects were divided according to sex and age (1 month group, 1 month to 3 years old group). The parameters were statistically analyzed, and the reference range of serum NSE in each age group was obtained. Results there was no significant difference in serum NSE level among 14 year old children (P 0.05), but there was significant difference in serum NSE level among different age groups (P 0.05). The reference ranges of three age groups were 0.32. 13 mg / L (January group) and 23. 26 mg / L (1 month to 3 years old group) and 0~21.47mg/L(3 group respectively. Conclusion there is significant difference in NSE reference interval among different age groups of children. The establishment of NSE reference interval of different ages is of great significance for the diagnosis and evaluation of clinical diseases.
【作者单位】：河南省郑州市儿童医院检验科;
【基金】：郑州市科技攻关项目(20140513)
【分类号】：R446.1;R725

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