中老年人群肺通气功能及其影响因素研究

发布时间：2018-07-03 16:31

本文选题：老年人 + 肺通气　；参考：《中华疾病控制杂志》2016年02期

【摘要】：目的探讨社会人口学和血生化指标对青岛地区50~74岁中老年人群的第1秒肺通气量(forced expiratory volumne in 1 second,FEV1)和最大肺通气量(the largest force vital capacity,FVC)的影响。方法采用分层整群抽样方法,2009年在青岛市区及农村抽取50~74岁居民2 476人,用自制量表进行调查,同时检测其FEV1、FVC和血生化指标。采用多元线性回归分析了年龄、性别、收入、教育、体质指数、糖化血红蛋白(glycosylated hemoglobin,Hb A1c)、总胆固醇(total cholesterol,TC)与高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)比值(TC/HDL-C)和尿酸(uric acid,UA)对肺通气功能的影响。结果男性的FEV1和FVC均高于女性。随着年龄增加,FEV1和FVC均出现下降,且在65~69段下降出现了加速。随着受教育(β=0.433,P=0.042)和BMI水平(β=0.776,P0.001)升高,FEV1也呈逐渐升高趋势。随着Hb A1c的升高,FEV1(β=-0.254,P0.001)和FVC(β=-0.298,P=0.046)均呈下降趋势,但随着TC/HDL-C的升高,FEV1和FVC又呈升高趋势。UA与FEV1和FVC之间均无显著性相关。结论 FEV1和FVC的下降是多因素作用的结果,其中年龄和Hb A1c是其危险因素,而收入、教育、BMI和血脂是其保护因素。
[Abstract]:Objective to investigate the effects of social demography and blood biochemical indexes on (forced expiratory volumne in 1 second FEV1 and (the largest force vital capacity1 in 50 ~ 74 years old population in Qingdao area. Methods A total of 2 476 residents aged 50 to 74 years were selected from urban and rural areas of Qingdao in 2009 by stratified cluster sampling, and their FEV1 FVC and blood biochemical indexes were measured by self-made scale. The effects of age, sex, income, education, body mass index, glycosylated hemoglobinine HbA1c, total cholesterol (total cholesterol) to high density lipoprotein cholesterol (HDL-C) ratio (TC / HDL-C) and uric acid (uric acidUA) on pulmonary ventilation function were analyzed by multiple linear regression analysis. Results both FEV1 and FVC in males were higher than those in females. Both FEV _ 1 and FVC decreased with age, and accelerated at 65 ~ 69. With the increase of education (尾 -0.433P _ (0.042) and BMI (尾 _ (0.776) P _ (0.001), FEV _ (1) also showed an increasing trend. With the increase of HbA1c, FEV1 (尾 -0.254 P0.001) and FVC (尾 -0.298P0. 046) showed a downward trend, but with the increase of Tc / HDL-C, FEV1 and FVC showed an increasing trend. There was no significant correlation between FEV1 and FVC. Conclusion the decrease of FEV1 and FVC is the result of multiple factors. Age and HbA1c are the risk factors, while income, educational BMI and blood lipids are the protective factors.
【作者单位】：赤峰市疾病预防控制中心公共卫生科;青岛市疾病预防控制中心老化研究项目组;
【基金】：国际合作项目丹麦科学技术和创新基金2009(08-045167) 山东省科学技术研究(2010G0020247)
【分类号】：R443.6

【相似文献】