住院患者多药耐药菌感染的临床分布特点与管理研究

发布时间：2018-07-03 19:11

本文选题：多药耐药菌 + 感染　；参考：《中华医院感染学杂志》2016年03期

【摘要】：目的探讨住院患者多药耐药菌感染的临床分布特点与管理策略,为多药耐药菌感染的预防与治疗提供依据。方法选取医院2012年1月-2014年12月351例多药耐药菌感染患者临床资料,采集标本进行菌株鉴定及药敏试验。结果 351例患者送检标本共分离出375株多药耐药菌,标本来源以痰液为主188株占50.13%,其次为血液68株占18.13%;呼吸内科、ICU、肾内科、胃肠肿瘤外科是多药耐药菌检出最多的科室,分别检出多药耐药菌115、72、60、51株,分别占30.67%、19.20%、16.00%、13.6%;375株多药耐药菌中革兰阴性菌276株73.60%、革兰阳性菌99株26.40%,检出率在前5位的分别为鲍氏不动杆菌、金黄色葡萄球菌、大肠埃希菌、铜绿假单胞菌和肺炎克雷伯菌;2012、2013、2014年多药耐药菌检出率,分别为28.80%、33.87%、37.33%,呈上升趋势。结论多药耐药菌感染呈上升趋势,应采取相应管理策略控制、预防感染,尤其对呼吸内科、ICU、肾内科、胃肠肿瘤外科等高危科室,更应该重视。
[Abstract]:Objective to investigate the clinical distribution and management strategy of multidrug resistant bacteria (MDR) infection in hospitalized patients, and to provide evidence for the prevention and treatment of MDR infection. Methods from January 2012 to December 2014, 351 patients with multidrug resistant bacteria infection were collected, and the strains were identified and drug sensitivity tests were carried out. Results 375 strains of multidrug resistant bacteria were isolated from 351 patients, 188 strains from sputum accounted for 50.13 strains, followed by 68 strains of blood accounted for 18.13.The ICU, Department of Renal Medicine, Department of Gastrointestinal Cancer was the most department to detect multidrug resistant bacteria. One hundred and fifty-one strains of multidrug resistant bacteria were detected, accounting for 30.67, respectively. Among them, 276 strains were Gram-negative bacteria, and 99 Gram-positive strains were 26.400.The positive rate was Acinetobacter baumannii, Staphylococcus aureus, Escherichia coli, Escherichia coli, and Escherichia coli, respectively. The detection rates of Pseudomonas aeruginosa and Klebsiella pneumoniae in 2014 were 28.80, 33.87 and 37.33, respectively, showing an upward trend. Conclusion the infection of multidrug resistant bacteria is on the rise and should be controlled by corresponding management strategies to prevent infection, especially to the high risk departments such as ICU, Nephrology, Gastrointestinal tumor surgery and so on, which should be paid more attention to.
【作者单位】：无锡市第四人民医院感染管理科;无锡市第四人民医院检验科;
【基金】：国家自然科学基金资助项目(31171217)
【分类号】：R446.5

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