产科医院感染临床特点与病原菌分析

发布时间：2018-07-21 12:50

【摘要】：目的探讨产科医院感染临床特点及病原菌种类、分布及耐药性,为产科医院感染的预防治疗提供参考依据。方法回顾性分析2014年5月-2015年5月于医院产科分娩的1 850例产妇临床资料,记录医院感染率、感染部位、病原菌构成及其耐药性,数据采用SPSS 19.0软件进行统计分析。结果 1 850例产妇发生医院感染31例,感染率1.7%;医院感染部位主要为上呼吸道,11例占35.5%;共分离出47株病原菌,以革兰阴性菌为主,共21株占44.7%,其次革兰阳性菌18株占38.3%,真菌8株占17.0%;革兰阴性菌对亚胺培南、美罗培南、环丙沙星耐药率较低,均25.0%;对其余抗菌药物均呈较高耐药率均50.0%。结论革兰阴性菌是产科医院感染病原菌的优势菌,掌握产科医院感染特点及病原菌耐药特征,并制定相应的干预措施,对提高产妇和新生儿预后具有重要作用。
[Abstract]:Objective to investigate the clinical characteristics, distribution and drug resistance of nosocomial infection in obstetrical department, and to provide reference for the prevention and treatment of nosocomial infection in obstetrics. Methods the clinical data of 1 850 parturients delivered in hospital from May 2014 to May 2015 were analyzed retrospectively. The nosocomial infection rate, infection site, pathogenic bacteria composition and drug resistance were recorded. SPSS 19.0 software was used to analyze the data. Results 31 cases of nosocomial infection occurred in 1 850 cases of parturient, the infection rate was 1.7%, 11 cases of nosocomial infection occurred mainly in upper respiratory tract and 35. 5%, 47 strains of pathogenic bacteria were isolated, mainly Gram-negative bacteria. A total of 21 strains accounted for 44.7 strains, followed by 18 Gram-positive bacteria (38.3%) and 8 fungi (17.0%); Gram-negative bacteria showed lower resistance to imipenem, meropenem and ciprofloxacin (25.0%); Conclusion Gram-negative bacteria are the dominant bacteria in obstetrical nosocomial infection. Mastering the characteristics of obstetrical nosocomial infection and drug resistance of pathogens, and formulating corresponding intervention measures, play an important role in improving the prognosis of parturient and newborn.
【作者单位】：温州市中心医院产科;温州市中心医院院感科;浙江大学医学院附属妇产科医院产科;
【基金】：浙江省医药卫生科技计划基金资助项目(2011KYA103)
【分类号】：R446.5

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