新生儿重症监护病房多重耐药菌感染危险因素logistic回归分析

发布时间：2018-08-14 10:32

【摘要】：目的分析新生儿重症监护病房(NICU)多重耐药菌感染的危险因素。方法回顾性分析2011年6月至2015年7月284例NICU住院患儿的临床资料,比较59例多重耐药菌感染与225例非多重耐药菌感染患儿的差异,并进行多因素logistic分析。结果 284例患儿均为单胎。59例多重耐药菌感染患儿,男42例、女17例,日龄(13.13±9.03)d;225例非多重耐药菌感染患儿,男175例、女50例,日龄(14.21±8.34)d。单因素分析显示,患儿胎龄、出生体质量、住院天数、出生时Apgar评分、机械通气、使用肠外营养、使用抗菌药物种类及持续时间8个因素是患儿多重耐药菌感染的危险因素(P??0.05);多因素分析显示,出生体质量、联合使用抗菌药物及抗菌药物使用持续时间是NICU患儿多重耐药菌感染的最主要因素(P??0.05)。结论应针对相关危险因素采取有效防控措施,减少NICU患儿多重耐药菌感染。
[Abstract]:Objective to analyze the risk factors of (NICU) multidrug resistant bacteria infection in neonatal intensive care unit. Methods the clinical data of 284 hospitalized children with NICU from June 2011 to July 2015 were analyzed retrospectively. The differences between 59 cases of multidrug resistant bacteria infection and 225 cases of non-multidrug resistant bacteria infection were compared, and multivariate logistic analysis was performed. Results 284 cases were single fetus, 59 cases of multidrug resistant bacteria infection, 42 cases were male, 17 cases were female, 225 cases of non-multidrug resistant bacteria infection were (13.13 卤9.03) dago, 175 cases were male, 50 cases were female, and (14.21 卤8.34) d old. Univariate analysis showed that: gestational age, birth weight, length of stay, Apgar score at birth, mechanical ventilation, parenteral nutrition, The risk factors of multidrug resistant bacteria infection in children were the kinds and duration of antibiotics (P0. 05), and the multivariate analysis showed that the birth weight was higher than that of the control group (P < 0. 05). Combined use of antibiotics and duration of use of antibiotics were the most important factors of multidrug resistant bacteria infection in children with NICU (P0. 05). Conclusion effective prevention and control measures should be taken to reduce multidrug resistant bacteria infection in children with NICU.
【作者单位】：贵州医科大学第三附属医院感染管理科;贵州医科大学第三附属医院微生物学实验室;
【基金】：贵州省黔南州社会发展科技项目(No.黔南科合社字[2013]20号)
【分类号】：R446.5;R197.323

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