三版国际脓毒症诊断标准诊断效能分析
发布时间:2018-08-23 19:05
【摘要】:目的探讨中国单个创伤重症医学科(ICU)中创伤后脓毒症患病率和相关危险因素,并评估1992、2001和2012国际脓毒症定义诊断创伤后脓毒症的效力。方法对大坪医院创伤ICU中符合入选标准的所有患者进行为期1d的横断面调查。调查数据包括人口学资料,临床特征,相关评分(APACHEⅡ、SOFA、GCS、ISS)和致伤机制。按照1992、2001和2012国际脓毒症指南脓毒症诊断标准中所有指标诊断脓毒症,分为A组、B组和C组,同时记录感染部位,感染病原菌,关键医学处置措施,明确感染证据,并追踪28d死亡发生率。选择痰、血液、伤口引流液(腹部、头颅和四肢)病原菌培养阳性作为诊断感染的确定性指标,计算3个版本的诊断灵敏度和特异度,并评估其诊断效能。结果共入选30例创伤患者,符合脓毒症诊断的A组23例,B组22例,C组20例,患病率分别为76.7%、73.3%、66.7%,3个诊断标准之间差异无统计学意义。28d死亡4例,均符合3个版本诊断标准,各组28d死亡发生率分别为17.4%、18.2%、25.0%,差异无统计学意义。A组诊断灵敏度为77.8%,特异度为25.0%;B组诊断灵敏度为82.2%,特异度为41.7%;C组诊断灵敏度为72.2%,特异度为41.7%。3个版本诊断效能之间差异无统计学意义。结论 3个版本的诊断标准对于创伤后脓毒症的诊断效能没有差异,1992年标准相对简单,可能更有利于创伤后脓毒症的诊断。
[Abstract]:Objective to investigate the prevalence and risk factors of post-traumatic sepsis in (ICU) of a single department of trauma intensive care in China, and to evaluate the effectiveness of the international definitions of sepsis in 1992 / 2001 and 2012 in the diagnosis of posttraumatic sepsis. Methods A 1-day cross-sectional survey was conducted among all the patients who met the inclusion criteria in ICU of Daping Hospital. The data included demographic data, clinical features, APACHE 鈪,
本文编号:2199636
[Abstract]:Objective to investigate the prevalence and risk factors of post-traumatic sepsis in (ICU) of a single department of trauma intensive care in China, and to evaluate the effectiveness of the international definitions of sepsis in 1992 / 2001 and 2012 in the diagnosis of posttraumatic sepsis. Methods A 1-day cross-sectional survey was conducted among all the patients who met the inclusion criteria in ICU of Daping Hospital. The data included demographic data, clinical features, APACHE 鈪,
本文编号:2199636
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