安徽省滁州市第一人民医院2014年临床分离菌的耐药性监测

发布时间：2018-08-31 17:08

【摘要】：目的了解安徽省滁州市第一人民医院临床分离菌的分布及耐药情况,为临床合理用药提供依据。方法回顾性分析2014年各类临床标本中分离菌的分布及耐药性。结果 2014年共分离病原菌1 697株,其中革兰阳性菌347株,占20.4%;革兰阴性菌1 350株,占79.6%。葡萄球菌属中耐甲氧西林金黄色葡萄球菌(MRSA)和耐甲氧西林凝固酶阴性葡萄球菌(MRCNS)的检出率分别为42.7%和87.0%。葡萄球菌属中未见对达托霉素、万古霉素和利奈唑胺的耐药株。肠球菌属中粪肠球菌和屎肠球菌对达托霉素、万古霉素和利奈唑胺均敏感。未发现对青霉素耐药的肺炎链球菌。大肠埃希菌、克雷伯菌属(肺炎克雷伯菌和产酸克雷伯菌)和奇异变形杆菌产超广谱β内酰胺酶(ESBL)的菌株分别占55.5%、22.2%和35.0%。肠杆菌科细菌对碳青霉烯类耐药率均低于20%。铜绿假单胞菌对碳青霉烯类、氨基糖苷类和哌拉西林-他唑巴坦的耐药率均低于30%。不动杆菌属对碳青霉烯类的耐药率均大于50%。结论 2014年该院分离的革兰阴性杆菌耐药性严重,应加强对其耐药性监测。
[Abstract]:Objective to investigate the distribution and drug resistance of clinical isolated bacteria in the first people's Hospital of Chuzhou City, Anhui Province. Methods the distribution and drug resistance of bacteria isolated from clinical specimens in 2014 were analyzed retrospectively. Results A total of 1,697 strains of pathogenic bacteria were isolated in 2014, of which 347 were Gram-positive bacteria (20.4%) and 1,350 Gram-negative bacteria (79.6%). The positive rates of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant coagulase-negative staphylococcus (MRCNS) were 42.7% and 87.0%, respectively. No resistant strains of Staphylococcus were found to be resistant to daptomycin, vancomycin and linazolamide. Enterococcus faecalis and Enterococcus faecium are sensitive to daptomycin, vancomycin and linazolamine. No penicillin resistant Streptococcus pneumoniae was found. Escherichia coli, Klebsiella (Klebsiella pneumoniae and Klebsiella acidogenic) and Proteus mirabilis producing extended-spectrum 尾 -lactamase (ESBL) accounted for 55.52.2% and 35.0% respectively. The resistance rate of Enterobacteriaceae to carbapenem was lower than 20%. The resistance rates of Pseudomonas aeruginosa to carbapenems, aminoglycosides and piperacillin-tazobactam were lower than 30%. The resistance rates of Acinetobacter to carbapenems were higher than 50%. Conclusion the drug resistance of Gram-negative bacilli isolated in 2014 is serious, and the surveillance of drug resistance should be strengthened.
【作者单位】：安徽省滁州市第一人民医院检验科;
【分类号】：R446.5

【相似文献】