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美罗培南与乌司他丁在重症感染患者治疗中的效果分析

发布时间:2018-09-06 12:24
【摘要】:目的探讨美罗培南与乌司他丁在急诊重症感染患者治疗中的应用效果,为临床治疗提供参考依据。方法选取2013年6月-2015年6月于医院接受治疗的急诊重症感染住院患者100例为研究对象,根据随机数字表法分成对照组和试验组,每组各50例,对照组采用美罗培南进行,并采用呼吸辅助、营养调节等措施;试验组在对照组的基础上同时给予乌司他丁进行治疗,比较两组患者临床指标,数据采用SPPS 18.0软件进行统计分析。结果治疗5d后,两组患者血清前降钙素原浓度、APACHEⅡ评分、肿瘤坏死因子-α(TNF-α)及高敏C-反应蛋白(hs-CRP)浓度均降低,且试验组降低程度明显大于对照组;对照组30d存活率明显低于试验组(P0.05)。结论急诊重症感染患者在使用美罗培南抗感染、运用呼吸辅助治疗、营养调节等有效措施的基础上,加用乌司他丁治疗,能有效改善其临床体征,减轻感染对机体的损伤,达到理想的重症感染治疗效果。
[Abstract]:Objective to investigate the efficacy of meropenem and ulinastatin in the treatment of emergency patients with severe infection. Methods from June 2013 to June 2015, 100 patients with severe infection were randomly divided into two groups: control group (n = 50) and experimental group (n = 50). The control group was treated with meropenem. The experimental group was treated with ulinastatin on the basis of the control group, and the clinical indexes of the two groups were compared. The data were analyzed by SPPS 18.0 software. Results after 5 days of treatment, the serum procalcitonin concentration and Apache 鈪,

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