河南省中医院血培养分离菌的分布及耐药性分析

发布时间：2018-09-06 12:03

【摘要】：目的了解河南省中医院近年来血培养阳性标本中分离菌的分布及耐药性,为临床合理选择用药提供依据。方法回顾性分析2012年1月—2014年12月该医院各科室送检的血培养阳性结果,药敏数据用WHONET 5.6软件进行分析。结果共收集住院患者血培养标本3 634份,培养阳性291份,阳性率为8.0%。291份阳性标本中,革兰阳性菌139株,占47.8%;革兰阴性菌120株,占41.2%;真菌32株,占11.0%。139株革兰阳性菌中前3位的是凝固酶阴性葡萄球菌(72株)、金黄色葡萄球菌(34株)和肠球菌属(21株);120株革兰阴性菌前3位的是大肠埃希菌(54株)、铜绿假单胞菌(28株)和肺炎克雷伯菌(25株);32株真菌中前3位的是近平滑念珠菌(14株)、白念珠菌(10株)和季也蒙念珠菌(5株)。未发现耐万古霉素和利奈唑胺的葡萄球菌和肠球菌。结论临床医师应高度重视并及时送检血培养,以便尽早确定病原菌,报告药敏结果,为临床医师提供准确的诊断与治疗依据,有效控制血流感染。
[Abstract]:Objective to investigate the distribution and drug resistance of isolated bacteria in blood culture positive specimens in Henan Hospital of traditional Chinese Medicine (TCM) in recent years so as to provide a basis for the rational choice of drug use in clinic. Methods the positive results of blood culture from January 2012 to December 2014 were analyzed retrospectively. The drug sensitivity data were analyzed by WHONET 5.6 software. Results A total of 3 634 blood culture specimens were collected from hospitalized patients, 291 of them were positive, the positive rate was 8.0%, 139 Gram-positive bacteria (47.8%), 120 Gram-negative bacteria (41.2%), 32 fungi (32 strains). Of the 11.0.139 Gram-positive strains, the top 3 were coagulase-negative staphylococci (72), Staphylococcus aureus (34) and Enterococcus (21), the top 3 strains were Escherichia coli (54), and Pseudomonas aeruginosa (28). Among the 32 strains of Klebsiella pneumoniae (25 strains), the top 3 strains were Candida albicans (14 strains), Candida albicans (10 strains) and Candida mongolicum (5 strains). Vancomycin resistant staphylococci and Enterococcus were not found. Conclusion clinicians should attach great importance to blood culture in time so as to identify pathogenic bacteria as soon as possible, report drug sensitivity results, provide accurate diagnosis and treatment basis for clinicians, and effectively control blood flow infection.
【作者单位】：河南省中医院检验科微生物室;
【基金】：河南省教育厅科学技术重点项目(14A320028)
【分类号】：R446.5

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