门诊美沙酮维持治疗影响因素及生命质量调查分析

发布时间：2018-11-04 08:42

【摘要】：目的探讨门诊美沙酮维持治疗(MMT)的相关影响因素及其对生命质量的影响。方法选取601例MMT患者作为研究对象,随访3年,依据最近1年服药天数分为对照组(n=101,服药天数≤150天)和治疗组(n=272,服药天数≥300天);采用多因素logistic回归法摸清MMT的相关危险因素,并分析维持治疗与否对生命质量的影响。结果MMT治疗依从性差的影响因素包括无职业(OR=3.010)、重度抑郁(OR=4.358)、社会支持度总分(OR=0.636)、日治疗剂量(OR=5.104)及尿检阳性(OR=2.574);治疗组的躯体功能分、心理功能分、社会功能分、戒断症状分及生命质量总分均明显高于对照组(P0.05)。结论 MMT较差者与无职业、重度抑郁、社会支持程度、治疗剂量低以及复吸海洛因密切相关,MMT有助于提高患者的生命质量。
[Abstract]:Objective to investigate the influencing factors and quality of life (QOL) of methadone maintenance therapy in outpatient patients with (MMT). Methods 601 patients with MMT were followed up for 3 years and divided into two groups: control group (n = 101) and treatment group (n = 272). Multivariate logistic regression was used to identify the risk factors associated with MMT and to analyze the effect of maintenance therapy on the quality of life (QOL). Results the influencing factors of poor compliance in MMT treatment included OR=3.010, OR=4.358, OR=0.636, OR=5.104 and OR=2.574. The factors influencing the poor compliance of MMT were as follows: no occupation (OR=3.010), severe depression (OR=4.358), total score of social support (OR=0.636), daily dose of treatment (OR=5.104) and positive urine test (OR=2.574). The scores of somatic function, psychological function, social function, withdrawal symptoms and total quality of life in the treatment group were significantly higher than those in the control group (P0.05). Conclusion the poor patients with MMT are closely related to non-occupation, severe depression, social support, low dosage of treatment and heroin resuscitation. MMT is helpful to improve the quality of life of the patients.
【作者单位】：武汉市武昌医院党政办;武汉市武昌医院公共卫生科;武汉市武昌医院健康门诊;
【基金】：武汉市卫计委项目(WG13C04)
【分类号】：R749.64

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