恶性肿瘤患者化疗后诱发口腔溃疡对心理状态的影响及预防分析

发布时间：2019-03-16 16:07

【摘要】：目的探讨恶性肿瘤患者化疗后诱发口腔溃疡对其心理状态的影响及预防措施。方法选取2013年2月至2015年1月收治的恶性肿瘤患者96例,根据化疗后是否诱发口腔溃疡分为观察组和对照组各48例,根据情况给予药物(复合维生素、康复新液等)、生理及心理干预,干预结束采用心理测评量表(SCL-90)、正性负性量表(PANAS)分析其心理及情绪状态,应用简明健康状况调查问卷(SF-36)、疼痛数字评分法(NRS)分析干预前后两组生活质量及疼痛度,并观察不良反应。结果干预前观察组SCL-90评分(253.78±5.64)分、PANAS负性情绪评分(46.32±1.11)分、NRS评分(8.31±0.55)分,高于对照组(P0.05),观察组PANAS正性情绪评分(15.97±1.32)分、SF-36评分(90.43±1.83)分低于对照组(P0.05),干预后两组SCL-90、PANAS正负性情绪、SF-36、NRS评分比较无显著差异(P0.05)。结论恶性肿瘤患者化疗后诱发口腔溃疡明显影响其心理与情绪状态,采用复合维生素、生理及心理干预可改善心理、情绪、生活质量及疼痛度,值得在临床推广。
[Abstract]:Objective to investigate the effect of oral ulcer induced by chemotherapy in patients with malignant tumor and its preventive measures. Methods from February 2013 to January 2015, 96 patients with malignant tumor were divided into observation group (n = 48) and control group (n = 48) according to whether or not they were induced by chemotherapy. Psychological and psychological intervention, psychological scale (SCL-90), positive and negative scale (PANAS) were used to analyze their psychological and emotional status, and SF-36 was used at the end of the intervention. (NRS) was used to analyze the quality of life and the degree of pain before and after intervention, and the adverse reactions were observed. Results before intervention, the scores of SCL-90, PANAS and NRS in the observation group were (253.78 卤5.64), (46.32 卤1.11) and (8.31 卤0.55) respectively, which were higher than those in the control group (P0.05). The PANAS positive emotion score (15.97 卤1.32) and the SF-36 score (90.43 卤1.83) in the observation group were lower than those in the control group (P0.05). After intervention, the SCL-90,PANAS positive and negative emotion, SF-36, in the two groups were significantly lower than those in the control group (P0.05). There was no significant difference in NRS score (P0.05). Conclusion Oral ulcer induced by chemotherapy in patients with malignant tumor significantly affects their psychological and emotional state. Multivitamin, physiological and psychological intervention can improve psychological, emotional, quality of life and pain. It is worth popularizing in clinical practice.
【作者单位】：郑州大学附属肿瘤医院;
【分类号】：R473.73

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