管网多相界面下抗生素抗性菌的分布特征研究

发布时间：2018-04-30 10:31

  本文选题：抗生素 + 多相界面　； 参考：《中国环境科学》2017年06期

【摘要】：以CDC生物膜反应器模拟给水管网输配系统,探究管网水相、生物膜相和颗粒物相三相界面下6种典型抗生素抗性细菌的分布特征.反应器稳定运行30d后,出水余氯从0.66mg/L下降到0.26mg/L,出水浊度和颗粒物浓度分别从进水的0.08NTU和377counts/mL增高至0.86NTU和4151counts/mL,出水水质变差.进水中仅有红霉素和氨苄西林的抗性细菌的数量较高,分别为36和99CFU/100mL,出水中,链霉素和氨苄西林的抗性细菌数量最高,分别为432和155CFU/100mL,远远高于进水中抗性细菌数量.生物膜相中异养菌总数和细胞总数达到了4089CFU/cm~2和1.5×10~6cells/cm~2,链霉素和红霉素的抗性细菌数量较高,为3432和2508CFU/cm~2,其抗性细菌比例分别达到了83.9%和61.4%.颗粒物相中,氯霉素和氨苄西林的抗性细菌比例较高,都在45%左右.生物膜和颗粒物都会给细菌提供一个安全稳定的生长场所,使细菌能够抵抗残留消毒剂和部分抗生素的抑制作用,更易产生耐药性,对人体健康的威胁也更大.
[Abstract]:The distribution system of water supply pipe network was simulated with CDC biofilm reactor, and the distribution characteristics of 6 typical antibiotic resistant bacteria in water phase, biofilm phase and particle phase interface were investigated. After the reactor operated steadily for 30d, the effluent chlorine was reduced from 0.66mg/L to 0.26mg/L, and the turbidity and particle concentration of the effluent were from the 0.08NTU and 377counts of the influent respectively. The water quality of /mL increased to 0.86NTU and 4151counts/mL. The number of resistant bacteria of only erythromycin and ampicillin was 36 and 99CFU/100mL, and the number of resistant bacteria in the water, streptomycin and ampicillin was the highest, 432 and 155CFU/100mL respectively, which was much higher than the number of resistant bacteria in the influent. The total number of bacteria and the total number of cells reached 4089CFU/cm~2 and 1.5 x 10~6cells/cm~2. The number of resistant bacteria of streptomycin and erythromycin was higher, 3432 and 2508CFU/cm~2, and the proportion of resistant bacteria reached 83.9% and 61.4%. particles respectively. The proportion of chloramphenicol and ampicillin resistant fine bacteria was higher, both around 45%. Biofilm and particulate matter. Bacteria can provide a safe and stable growth place for bacteria to resist the inhibitory effects of residual disinfectants and some antibiotics, more susceptible to resistance, and more threat to human health.

【作者单位】： 北京工商大学环境科学与工程系;军事医学科学院疾病预防控制所;
【基金】：国家自然科学基金资助项目(51408010,51608011) 北京工商大学两科基金培育项目(LKJJ2016-17)
【分类号】：TU991.25
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本文编号：1824204