以滤纸为模板合成新型介孔生物活性玻璃微管材料
发布时间：2018-07-31 07:10
【摘要】：用快速滤纸为生物模板,通过先浸渍后焙烧的方法合成了介孔生物活性玻璃微管材料。快速滤纸的管状结构被完美复制,其管壁为生成的介孔生物玻璃材料。通过在合成过程中引入铁元素可以使材料具有一定的磁性。材料的形貌、结构和磁性通过扫描电镜、粉末X射线衍射、透射电镜、氮气吸附-脱附曲线,红外光谱和磁滞回线进行了表征。并且通过模拟体液浸泡方法考察了其矿化能力,以地塞米松为模型药物考察其释药能力和生物相容性。合成的介孔生物活性玻璃微管材料具有复杂的管状多级结构、快速的矿化能力和良好的生物相容性,并具备一定的磁性,是一种不可多得的药物缓释材料。
[Abstract]:Mesoporous bioactive glass microtubule material is synthesized by rapid filter paper as a biological template. The mesoporous bioactive glass microtubule material is synthesized by impregnating and roasting first. The tubular structure of the fast filter paper is perfectly replicated, and its tube wall is a mesoporous biological glass material. By introducing iron element in the process of synthesis, the material has a certain magnetic properties. The morphology and structure of the material are made. And magnetic properties were characterized by scanning electron microscopy, powder X ray diffraction, transmission electron microscopy, nitrogen adsorption desorption curve, infrared spectrum and hysteresis loop, and its mineralizing ability was investigated by simulated body fluid immersion method. The release ability and biocompatibility of the model drug were investigated with dexamethasone. The mesoporous bioactive glass microspheres were synthesized. Tube material has complex tubular multistage structure, rapid mineralization ability and good biocompatibility, and has a certain magnetic properties. It is a rare drug release material.
【作者单位】： 吉林大学食品科学与工程学院;
【基金】：国家自然科学基金(No.31402251) 教育部高等学校博士学科点专项科研基金(No.20130061120116)资助项目
【分类号】：TB383.4;TQ460.1
本文编号：2154822
[Abstract]:Mesoporous bioactive glass microtubule material is synthesized by rapid filter paper as a biological template. The mesoporous bioactive glass microtubule material is synthesized by impregnating and roasting first. The tubular structure of the fast filter paper is perfectly replicated, and its tube wall is a mesoporous biological glass material. By introducing iron element in the process of synthesis, the material has a certain magnetic properties. The morphology and structure of the material are made. And magnetic properties were characterized by scanning electron microscopy, powder X ray diffraction, transmission electron microscopy, nitrogen adsorption desorption curve, infrared spectrum and hysteresis loop, and its mineralizing ability was investigated by simulated body fluid immersion method. The release ability and biocompatibility of the model drug were investigated with dexamethasone. The mesoporous bioactive glass microspheres were synthesized. Tube material has complex tubular multistage structure, rapid mineralization ability and good biocompatibility, and has a certain magnetic properties. It is a rare drug release material.
【作者单位】： 吉林大学食品科学与工程学院;
【基金】：国家自然科学基金(No.31402251) 教育部高等学校博士学科点专项科研基金(No.20130061120116)资助项目
【分类号】：TB383.4;TQ460.1
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