非环状卤胺抗菌材料的合成及其性能研究
发布时间：2018-08-03 20:20
【摘要】：随着生活水平的提高,人们对自身生活健康的要求也越来越高,但日常生活中,微生物污染给人们生命安全造成的威胁时有发生,因此开发新型抗菌材料来保障人们生活的卫生和安全变得尤为重要。目前,卤胺抗菌材料由于其强大的抗菌功效、抗菌官能团的可再生性和抗菌的广谱性而引起研究者的广泛兴趣,但非环状卤胺抗菌材料的研究较少,本文合成了一种非环状卤胺聚合物大孔交联抗菌树脂,制备了一种非环状卤胺接枝棉纤维材料。主要研究内容如下:(1)非环状卤胺聚合物大孔交联抗菌树脂的合成及其性能研究以甲基丙烯酰胺为单体,亚甲基双丙烯酰胺和环氧氯丙烷为交联剂,通过悬浮聚合合成了一种非环状卤胺前置体聚合物大孔交联树脂P(AA-MBA-EPI),再经过在次氯酸钠溶液中的氯化反应,得到了一种非环状卤胺聚合物大孔交联树脂P(AA-MBA-EPI-Cl)。通过场发射扫描电镜(FE-SEM)、红外光谱(FTIR)、Brunauer-Emmet-Teller(BET)分析、X射线能谱(XPS)对材料进行了表征。BET分析和氧化态氯含量测试表明:制备的P(AA-MBA-EPI-Cl)的比表面积可达到135.2m2/g,且氧化态氯含量可高达10.05%,非常适用于饮用水的快速杀菌消毒。抗菌性能测试表明:制备的P(AA-MBA-EPI-Cl)可在1 min之内全部杀死浓度为1×106 CFU/mL的大肠杆菌和金黄的葡萄球菌。另外,我们还对制备的P(AA-MBA-EPI-Cl)中的卤胺抗菌官能团的再生性能和储存稳定性进行了初步的评价。(2)非环状卤胺接枝棉纤维材料的制备及其性能与研究在水相中通过一种高效的固相催化反应使亚甲基双丙烯酰胺(MBA)以共价键的形式接枝到棉纤维表面,接枝后的棉纤维(棉布-MBA)通过场发射扫描电镜和红外光谱分析得到了表征。经过在稀释的次氯酸钠溶液中氯化后,棉布-MBA上的酰胺官能团转化成了卤胺官能团,即得到了耐洗性好的非环状卤胺抗菌棉纤维(棉布-MBA-Cl)。抗菌性能测试表明,棉布-MBA-Cl可在1 min内完全杀死浓度为5.78×107 CFU/m L的金黄色的葡萄球菌和浓度为7.58×108 CFU/m L的大肠杆菌。洗脱性能测试显示,经过50次的洗脱循环后,棉布-MBA-Cl仍然含有0.06%的氧化态氯,且经过再次氯化后,其氧化态氯含量可达到0.30%。这表明棉布-MBA-Cl上的卤胺官能团和棉布与MBA之间形成的共价键都具有良好的耐水洗性能。储存稳定性测试显示,经过三十天的储存,棉布-MBA-Cl的氯含量从0.43%降到了0.32%,表明棉布-MBA-Cl上的卤胺官能团在室温下具有良好的储存稳定性。并且,由于对棉纤维的接枝和氯化条件都比较温和,对棉布-MBA-Cl的拉伸强度测试表明,接枝和氯化过程对棉纤维结构没有造成明显的破坏。
[Abstract]:With the improvement of living standards, people have higher and higher requirements for their own health, but in daily life, the threat of microbial pollution to people's lives occurs from time to time. Therefore, the development of new antimicrobial materials to protect people's lives of health and safety has become particularly important. At present, halogen amine antimicrobial materials have attracted extensive interest due to their strong antibacterial efficacy, antibacterial functional group reproducibility and antimicrobial broad-spectrum, but less research has been done on non-cyclic halogenamine antimicrobial materials. In this paper, a macroporous cross-linked antibacterial resin was synthesized and a non-cyclic halogen amine graft cotton fiber material was prepared. The main research contents are as follows: (1) Synthesis and properties of macroporous antibacterial resin of non-cyclic halogenamine polymer; Methyl acrylamide as monomer, methylene bisacrylamide and epichlorohydrin as crosslinker, A kind of macroporous crosslinked resin P (AA-MBA-EPI) was synthesized by suspension polymerization. After chlorination in sodium hypochlorite solution, a macroporous cross-linked resin P (AA-MBA-EPI-Cl) was obtained. Field emission scanning electron microscopy (FE-SEM), (FTIR) Brunauer-Emmet-Teller (BET) analysis and X-ray energy dispersive (XPS) were used to characterize the materials. The results showed that the specific surface area of the prepared P (AA-MBA-EPI-Cl) was 135.2 m2 / g, and the oxidized chlorine content could reach 10.05%. Very suitable for rapid disinfection of drinking water. The antimicrobial activity test showed that the prepared P (AA-MBA-EPI-Cl) could completely kill Escherichia coli and Staphylococcus aureus with a concentration of 1 脳 10 ~ 6 CFU/mL within 1 min. In addition, We also evaluated the regeneration and storage stability of halogenamine antibacterial functional groups in P (AA-MBA-EPI-Cl). (2) preparation of acyclic halogen grafted cotton fiber materials and their properties and studies in aqueous phase. The solid phase catalytic reaction made methylene bisacrylamide (MBA) grafted to the surface of cotton fiber in the form of covalent bond. The grafted cotton fiber (cotton-MBA) was characterized by field emission scanning electron microscopy and infrared spectroscopy. After chlorination in dilute sodium hypochlorite solution, the amide functional group on cotton cloth / MBA was converted into halogen functional group, and a washable non-cyclic haloamine antibacterial cotton fiber (cotton cloth MBA-Cl) was obtained. The antibacterial activity test showed that cotton cloth MBA-Cl could completely kill the Staphylococcus aureus and Escherichia coli at the concentration of 5.78 脳 10 ~ 7 CFU/m / L and 7.58 脳 10 ~ 8 CFU/m / L within 1 min. After 50 elution cycles, the cotton cloth MBA-Cl still contains 0.06% of oxidized chlorine, and after re-chlorination, the content of oxidized chlorine can reach 0.30%. The results show that the halogen functional groups on cotton cloth MBA-Cl and the covalent bonds formed between cotton cloth and MBA have good washing resistance. The storage stability test showed that the chlorine content of cotton cloth MBA-Cl decreased from 0.43% to 0.32% after 30 days storage, which indicated that the halogen functional groups on cotton cloth MBA-Cl had good storage stability at room temperature. Because of the mild grafting and chlorination conditions of cotton fiber, the tensile strength test of cotton cloth MBA-Cl shows that the grafting and chlorination process have no obvious damage to the cotton fiber structure.
【学位授予单位】：上海师范大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：TB34
本文编号：2162896
[Abstract]:With the improvement of living standards, people have higher and higher requirements for their own health, but in daily life, the threat of microbial pollution to people's lives occurs from time to time. Therefore, the development of new antimicrobial materials to protect people's lives of health and safety has become particularly important. At present, halogen amine antimicrobial materials have attracted extensive interest due to their strong antibacterial efficacy, antibacterial functional group reproducibility and antimicrobial broad-spectrum, but less research has been done on non-cyclic halogenamine antimicrobial materials. In this paper, a macroporous cross-linked antibacterial resin was synthesized and a non-cyclic halogen amine graft cotton fiber material was prepared. The main research contents are as follows: (1) Synthesis and properties of macroporous antibacterial resin of non-cyclic halogenamine polymer; Methyl acrylamide as monomer, methylene bisacrylamide and epichlorohydrin as crosslinker, A kind of macroporous crosslinked resin P (AA-MBA-EPI) was synthesized by suspension polymerization. After chlorination in sodium hypochlorite solution, a macroporous cross-linked resin P (AA-MBA-EPI-Cl) was obtained. Field emission scanning electron microscopy (FE-SEM), (FTIR) Brunauer-Emmet-Teller (BET) analysis and X-ray energy dispersive (XPS) were used to characterize the materials. The results showed that the specific surface area of the prepared P (AA-MBA-EPI-Cl) was 135.2 m2 / g, and the oxidized chlorine content could reach 10.05%. Very suitable for rapid disinfection of drinking water. The antimicrobial activity test showed that the prepared P (AA-MBA-EPI-Cl) could completely kill Escherichia coli and Staphylococcus aureus with a concentration of 1 脳 10 ~ 6 CFU/mL within 1 min. In addition, We also evaluated the regeneration and storage stability of halogenamine antibacterial functional groups in P (AA-MBA-EPI-Cl). (2) preparation of acyclic halogen grafted cotton fiber materials and their properties and studies in aqueous phase. The solid phase catalytic reaction made methylene bisacrylamide (MBA) grafted to the surface of cotton fiber in the form of covalent bond. The grafted cotton fiber (cotton-MBA) was characterized by field emission scanning electron microscopy and infrared spectroscopy. After chlorination in dilute sodium hypochlorite solution, the amide functional group on cotton cloth / MBA was converted into halogen functional group, and a washable non-cyclic haloamine antibacterial cotton fiber (cotton cloth MBA-Cl) was obtained. The antibacterial activity test showed that cotton cloth MBA-Cl could completely kill the Staphylococcus aureus and Escherichia coli at the concentration of 5.78 脳 10 ~ 7 CFU/m / L and 7.58 脳 10 ~ 8 CFU/m / L within 1 min. After 50 elution cycles, the cotton cloth MBA-Cl still contains 0.06% of oxidized chlorine, and after re-chlorination, the content of oxidized chlorine can reach 0.30%. The results show that the halogen functional groups on cotton cloth MBA-Cl and the covalent bonds formed between cotton cloth and MBA have good washing resistance. The storage stability test showed that the chlorine content of cotton cloth MBA-Cl decreased from 0.43% to 0.32% after 30 days storage, which indicated that the halogen functional groups on cotton cloth MBA-Cl had good storage stability at room temperature. Because of the mild grafting and chlorination conditions of cotton fiber, the tensile strength test of cotton cloth MBA-Cl shows that the grafting and chlorination process have no obvious damage to the cotton fiber structure.
【学位授予单位】：上海师范大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：TB34
【参考文献】
相关期刊论文 前1条
1 姜永军;饮用水消毒技术[J];甘肃科技;2004年05期
，本文编号：2162896
本文链接：https://www.wllwen.com/kejilunwen/cailiaohuaxuelunwen/2162896.html
