基于DNA分子的纳米功能材料的设计、组装及应用
发布时间：2018-09-05 13:04
【摘要】：DNA除了作为一种遗传信息的载体分子之外,还可以通过折叠或组装从而形成特定的二维和三维结构。通过设计DNA分子的结构并探索其与纳米材料之间的相互作用的研究已经引起了国内外学术界的持续关注。DNA功能化的无机纳米材料促进了分析科学、生命科学以及环境科学的快速发展。本文将从疾病分子机制研究、疾病诊断和疾病治疗三个角度出发,探究面向生物医学分析应用的DNA分子功能化的无机纳米材料的设计与组装。除此之外,还对DNA功能化纳米材料技术的发展前景进行了展望。
[Abstract]:In addition to being a carrier of genetic information, DNA can be folded or assembled to form specific two-dimensional and three-dimensional structures. By designing the structure of DNA molecules and exploring the interaction between DNA molecules and nanomaterials, the research on the interaction between DNA molecules and nanomaterials has attracted the sustained attention of academic circles both at home and abroad, and has promoted the analytical science of inorganic nanomaterials. The rapid development of life science and environmental science. In this paper, we will explore the design and assembly of DNA molecular functionalized inorganic nanomaterials for biomedical analysis from the perspectives of disease molecular mechanism, disease diagnosis and disease treatment. In addition, the prospect of DNA functionalized nanomaterials is prospected.
【作者单位】： 武汉大学化学与分子科学学院;
【基金】：国家自然科学基金项目(51272186,21422105,21675120) 全国优秀博士学位论文作者专项资金项目(201220) 湖北省自然科学基金项目(2015CFA032)资助
【分类号】：Q523;TB383.1
，
本文编号：2224361
[Abstract]:In addition to being a carrier of genetic information, DNA can be folded or assembled to form specific two-dimensional and three-dimensional structures. By designing the structure of DNA molecules and exploring the interaction between DNA molecules and nanomaterials, the research on the interaction between DNA molecules and nanomaterials has attracted the sustained attention of academic circles both at home and abroad, and has promoted the analytical science of inorganic nanomaterials. The rapid development of life science and environmental science. In this paper, we will explore the design and assembly of DNA molecular functionalized inorganic nanomaterials for biomedical analysis from the perspectives of disease molecular mechanism, disease diagnosis and disease treatment. In addition, the prospect of DNA functionalized nanomaterials is prospected.
【作者单位】： 武汉大学化学与分子科学学院;
【基金】：国家自然科学基金项目(51272186,21422105,21675120) 全国优秀博士学位论文作者专项资金项目(201220) 湖北省自然科学基金项目(2015CFA032)资助
【分类号】：Q523;TB383.1
，
本文编号：2224361
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