一种生物芯片检测平台的控制系统的设计
发布时间：2018-09-01 14:45
【摘要】：生物芯片(biochip)技术是随着人类基因组计划(human genome project,HGP)发展起来的一门前沿高新技术,在基因检测,药物筛选,临床等多个领域有广阔发展前景。当下,生物芯片光学检测法以其灵敏度高、分析速度快、式样用量少、成本低、易于微型化、便携化等特点而受到广泛关注。本文就生物芯片检测平台的控制系统进行深入研究,设计一种基于ARM9处理器为硬件,Linux系统为底层软件的嵌入式生物芯片检测平台。硬件上,7寸触摸屏作为操作界面,机箱主体为四组电机,分别是XY滑动平台电机、注射泵电机、LLS光源电机,分别控制待测物的位置、注射样本液体、LLS光源位置,另外,还包括辅助开关控制,分别是内部照明开关、震动电机开关、泄流阀开关以及LLS光源开关。软件上,采用Linux系统作为底层操作系统,移植Qt SDK作为GUI界面开发套件,PC端用Ubuntu Linux 12.04作为开发环境。界面总体分为状态栏和功能区,功能区又细分为非机械控制、机械控制、校正、测试以及帮助子模块,具体实现方法涉及到GPIO、UART、IIC以及SPI等编程。文章将按照架构设计,硬件搭建,软件编程,数据处理的顺序去详细阐述生物芯片检测平台的控制系统的设计过程,着重说明软件控制的具体实现方法。本文是基于国际合作项目“纳米量子点蛋白质生物芯片关键技术及产品研发”,在着手写本文之前作者已经完成了一代生物芯片检测平台的控制系统的设计,整个系统的机械控制,开关控制,数据采集与处理,GUI界面的交互等一系列功能都可以实现,并且能够稳定运行。本文的研究将为进一步研发二代系统以及制备纳米量子点蛋白质芯片奠定了基础,推进项目的研发进程。
[Abstract]:Biochip (biochip) technology is a new and advanced technology developed with the Human Genome Project (human genome project,HGP). It has broad prospects in gene detection, drug screening, clinical and other fields. Nowadays, biochip optical detection method has been widely concerned because of its high sensitivity, fast analysis speed, low cost, easy miniaturization and portability. In this paper, the control system of biochip detection platform is deeply studied, and an embedded biochip detection platform based on ARM9 processor is designed. The hardware has a 7-inch touch screen as the operating interface, and the main body of the chassis is four groups of motors, namely, the XY sliding platform motor, the injection pump motor and the LLS light source motor, which respectively control the position of the object to be tested and the position of the injection sample liquid to the LLS light source. In addition, It also includes auxiliary switch control, such as internal lighting switch, vibration motor switch, drain valve switch and LLS light source switch. In software, Linux system is used as the underlying operating system, Qt SDK is transplanted as GUI interface development kit, and Ubuntu Linux 12.04 is used as the development environment. The interface is divided into status bar and function area, and the function area is subdivided into non-mechanical control, correction, test and help sub-module. The implementation method involves GPIO,UART,IIC and SPI programming. According to the sequence of architecture design, hardware construction, software programming and data processing, the design process of the control system of the biochip detection platform is described in detail in this paper, with emphasis on the realization method of software control. This paper is based on the international cooperation project "the key technology and product development of protein biochip of nanometer quantum dot". Before writing this paper, the author has completed the design of the control system of the biochip detection platform. A series of functions, such as mechanical control, switch control, data acquisition and processing GUI interface, can be realized and can run stably. The research in this paper will lay a foundation for the further research and development of the second generation system and the preparation of nanoscale quantum dot protein chip, and promote the research and development process of the project.
【学位授予单位】：贵州大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：TN407
，
本文编号：2217521
[Abstract]:Biochip (biochip) technology is a new and advanced technology developed with the Human Genome Project (human genome project,HGP). It has broad prospects in gene detection, drug screening, clinical and other fields. Nowadays, biochip optical detection method has been widely concerned because of its high sensitivity, fast analysis speed, low cost, easy miniaturization and portability. In this paper, the control system of biochip detection platform is deeply studied, and an embedded biochip detection platform based on ARM9 processor is designed. The hardware has a 7-inch touch screen as the operating interface, and the main body of the chassis is four groups of motors, namely, the XY sliding platform motor, the injection pump motor and the LLS light source motor, which respectively control the position of the object to be tested and the position of the injection sample liquid to the LLS light source. In addition, It also includes auxiliary switch control, such as internal lighting switch, vibration motor switch, drain valve switch and LLS light source switch. In software, Linux system is used as the underlying operating system, Qt SDK is transplanted as GUI interface development kit, and Ubuntu Linux 12.04 is used as the development environment. The interface is divided into status bar and function area, and the function area is subdivided into non-mechanical control, correction, test and help sub-module. The implementation method involves GPIO,UART,IIC and SPI programming. According to the sequence of architecture design, hardware construction, software programming and data processing, the design process of the control system of the biochip detection platform is described in detail in this paper, with emphasis on the realization method of software control. This paper is based on the international cooperation project "the key technology and product development of protein biochip of nanometer quantum dot". Before writing this paper, the author has completed the design of the control system of the biochip detection platform. A series of functions, such as mechanical control, switch control, data acquisition and processing GUI interface, can be realized and can run stably. The research in this paper will lay a foundation for the further research and development of the second generation system and the preparation of nanoscale quantum dot protein chip, and promote the research and development process of the project.
【学位授予单位】：贵州大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：TN407
，
本文编号：2217521
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