微流控振荡器的设计与特性研究
发布时间：2018-09-06 17:18
【摘要】：微流控技术是一门主要研究微/纳米量级结构对微/纳升体积流体进行精确控制的科学。随着微流控技术的不断发展以及微流控芯片的复杂化,增加微流控技术的功能和实用性迫在眉睫,其关键就在于开发标准化、可扩展和通用的控制系统以及交变流体驱动源。流体控制的微流控振荡器促使嵌入式非电气控制系统的发展,提高了微流控系统的便捷性、可扩展性和鲁棒性,为微流控芯片迈入数字化领域打下基础。本文以电路中的非稳态多谐振荡器为原型,利用微流控等效电路理论,设计并研究了一款流体驱动的微流控振荡器。该微流控振荡器由流道和常闭阀对称级联而成,外部辅助装置简单、可移植性强。1.利用微流控等效电路理论,对微流控系统中单向阀、常闭阀、流阻串并联、流阻星三角变换以及复杂网络的KVL、KCL进行等效分析,证实了利用等效电路理论辅助设计微流控系统的方便、快捷和高效。2.利用COMSOL仿真平台,发展了一种微流控振荡器的仿真技术。针对微流道流阻、流容、流感以及常闭阀的特性进行了仿真研究,并与等效电路理论进行对比,验证了仿真的可行性和准确性,完备了微流控仿真技术,为微流控振荡器的数值模拟研究打下基础。3.从微流控振荡器的工作原理中得到该振荡器工作频率的相关参数:常闭阀的内置流容和反馈流阻。利用仿真软件对微流控振荡器的模型进行模拟研究,主要研究了(1)微流控振荡器的振荡周期与流体入口流速、反馈流阻以及常闭阀阈值压力的变化关系,(2)振荡波形的上升沿、下降沿与入口流量和常闭阀的关系,(3)振荡周期占空比与阀座的关系,最后(4)分析了微流控振荡器的谐振频率。研究结果表明,随着入口流速的增加,振荡周期减小;阀的阈值与振荡周期呈线性关系,随着常闭阀阀座的增宽或阀的宽长比减小,周期变长;随着反馈流阻的增大,周期变长;增大入口流速或减小常闭阀的入口流容可以缩短上升沿时间;振荡器结构的不对称设计可以调节周期的占空比。另外,根据所得的微流控振荡器的谐振频率(196Hz)与工作频率(0.02Hz),证实该模型的等效流感可以忽略。根据研究结果,可以按照不同的要求,设计出相应的微流控振荡器。
[Abstract]:Microfluidic technology is a science that focuses on the precise control of micro / nanostructured micro / nano volume fluids. With the development of microfluidic technology and the complication of microfluidic chip, it is urgent to increase the function and practicability of microfluidic technology. The key lies in developing standardized, extensible and universal control system and alternating fluid drive source. The fluid-controlled microfluidic oscillator promotes the development of embedded non-electrical control system, and improves the convenience, expansibility and robustness of the microfluidic system, which lays the foundation for the microfluidic chip to enter the digital field. In this paper, a fluid driven microfluidic oscillator is designed and studied using the theory of microfluidic equivalent circuit based on the unsteady multivibrator in the circuit. The microfluidic oscillator consists of a symmetrical cascade of flow channels and closed valves. The external auxiliary device is simple and portability is strong. 1. Based on the equivalent circuit theory of microfluidic system, the equivalent analysis of unidirectional valve, closed valve, series and parallel flow resistance, triangulation of flow resistance and KVL,KCL of complex network is carried out. It is proved that the design of microfluidic system with equivalent circuit theory is convenient, fast and efficient. A microfluidic oscillator simulation technology is developed using COMSOL simulation platform. The characteristics of microchannel flow resistance, flow volume, flu and closed valve are simulated, and compared with equivalent circuit theory, the feasibility and accuracy of simulation are verified, and the simulation technology of microfluidic control is completed. It lays a foundation for numerical simulation of microfluidic oscillator. From the operating principle of the microfluidic oscillator, the parameters related to the frequency of the oscillator are obtained: the built-in flow volume and the feedback flow resistance of the normally closed valve. The simulation software is used to simulate the model of the microfluidic oscillator. The relationship between the oscillation period of the microfluidic oscillator and the inlet velocity of the fluid, the feedback flow resistance and the threshold pressure of the closed valve is studied. (2) the rising edge of the oscillation waveform. The relationship between the descent edge and the inlet flow rate and the closed valve, (3) the relationship between the period duty cycle and the valve seat, and (4) the resonant frequency of the microfluidic oscillator is analyzed. The results show that the oscillation period decreases with the increase of inlet velocity, the threshold value of the valve is linearly related to the oscillation period, and the period becomes longer with the widening of the valve seat or the ratio of the width to length of the valve, and with the increase of the feedback flow resistance. The rising edge time can be shortened by increasing the inlet velocity or decreasing the inlet flow volume of the closed valve, and the period duty cycle can be adjusted by the asymmetric design of the oscillator structure. In addition, according to the resonant frequency (196Hz) and the operating frequency (0.02Hz) of the microfluidic oscillator, it is proved that the equivalent influenza of the model can be neglected. According to the research results, the corresponding microfluidic oscillator can be designed according to different requirements.
【学位授予单位】：南京邮电大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：TN752
本文编号：2227021
[Abstract]:Microfluidic technology is a science that focuses on the precise control of micro / nanostructured micro / nano volume fluids. With the development of microfluidic technology and the complication of microfluidic chip, it is urgent to increase the function and practicability of microfluidic technology. The key lies in developing standardized, extensible and universal control system and alternating fluid drive source. The fluid-controlled microfluidic oscillator promotes the development of embedded non-electrical control system, and improves the convenience, expansibility and robustness of the microfluidic system, which lays the foundation for the microfluidic chip to enter the digital field. In this paper, a fluid driven microfluidic oscillator is designed and studied using the theory of microfluidic equivalent circuit based on the unsteady multivibrator in the circuit. The microfluidic oscillator consists of a symmetrical cascade of flow channels and closed valves. The external auxiliary device is simple and portability is strong. 1. Based on the equivalent circuit theory of microfluidic system, the equivalent analysis of unidirectional valve, closed valve, series and parallel flow resistance, triangulation of flow resistance and KVL,KCL of complex network is carried out. It is proved that the design of microfluidic system with equivalent circuit theory is convenient, fast and efficient. A microfluidic oscillator simulation technology is developed using COMSOL simulation platform. The characteristics of microchannel flow resistance, flow volume, flu and closed valve are simulated, and compared with equivalent circuit theory, the feasibility and accuracy of simulation are verified, and the simulation technology of microfluidic control is completed. It lays a foundation for numerical simulation of microfluidic oscillator. From the operating principle of the microfluidic oscillator, the parameters related to the frequency of the oscillator are obtained: the built-in flow volume and the feedback flow resistance of the normally closed valve. The simulation software is used to simulate the model of the microfluidic oscillator. The relationship between the oscillation period of the microfluidic oscillator and the inlet velocity of the fluid, the feedback flow resistance and the threshold pressure of the closed valve is studied. (2) the rising edge of the oscillation waveform. The relationship between the descent edge and the inlet flow rate and the closed valve, (3) the relationship between the period duty cycle and the valve seat, and (4) the resonant frequency of the microfluidic oscillator is analyzed. The results show that the oscillation period decreases with the increase of inlet velocity, the threshold value of the valve is linearly related to the oscillation period, and the period becomes longer with the widening of the valve seat or the ratio of the width to length of the valve, and with the increase of the feedback flow resistance. The rising edge time can be shortened by increasing the inlet velocity or decreasing the inlet flow volume of the closed valve, and the period duty cycle can be adjusted by the asymmetric design of the oscillator structure. In addition, according to the resonant frequency (196Hz) and the operating frequency (0.02Hz) of the microfluidic oscillator, it is proved that the equivalent influenza of the model can be neglected. According to the research results, the corresponding microfluidic oscillator can be designed according to different requirements.
【学位授予单位】：南京邮电大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：TN752
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