几种海洋抗污损化合物的单一与联合毒性效应评价

发布时间：2018-03-27 22:36

本文选题：海洋生物学　切入点：海洋抗污损化合物　出处：《应用海洋学学报》2017年03期

【摘要】：本文研究了目前广泛应用的防污涂料毒性添加剂3-(3,4-dichlorophenyl)-1,1-dimethylurea(Diuron)、2-methylthio-4-t-butylamino-6-cyclopropylamino-s-triazine(Irgarol 1051)、triphenylborane pyridine(TPBP)、Zinc pyrithione(Zn-Pt)、Zinc bis(dimethyl thiocarbamate,Ziram)、Cu~(2+)的单一毒性和二元混合毒性.结果表明:对卤虫而言,6种化合物单一毒性按强弱排序为TPBPDiuronZiramCuSO_4Irgarol 1051Zn-Pt,它们对卤虫48 h的LC50分别为CuSO_49.1μg/cm~3、Diuron 8.0μg/cm~3、Irgarol 1051 12.0μg/cm~3、TPBP 0.07μg/cm~3、Zn-Pt 30.9μg/cm~3、Ziram 8.2μg/cm~3.对卤虫的二元联合毒性实验采用混合毒性指数法(MTI)评价,结果显示:共有8个组合具有协同效应,包括Irgarol 1051/Diuron、Irgarol 1051/TPBP、Irgarol 1051/Ziram、Irgarol 1051/Zn-Pt、Irgarol 1051/CuSO4、Diuron/TPBP、Ziram/CuSO_4以及Zn-Pt/CuSO_4.其中Irgarol 1051/Ziram组合的MTI值高达2.740,Zn-Pt/CuSO_4组合更高达5.621.发现8个协同效应组合中有5个和Irgarol 1051有关,表明Irgarol 1051在基于毒性的防污涂料配方中有其良好的适应性,但进入海洋环境的Irgarol 1051具有引起较强生物毒性的环境风险.另有5个组合Diuron/Zn-Pt、Diuron/CuSO_4、TPBP/Ziram、TPBP/ZnPt、Ziram/Zn-Pt表现为一定程度拮抗作用,应在防污涂料配制中尽量避免同时使用.
[Abstract]:In this paper, the single toxicity and binary toxicity of the widely used antifouling coating toxic additive 3-trioxy 4-dichlorophenyl-1-dimethylurea1 (2-methylthio-4-t-butylamino-6-cyclopropylamino-6-cyclopropylamino-s-triazine) Irgarol 1051 borane pyrithione Zn-Ptthionium zinc bis(dimethyl thiocarbamateZiramamateZiramamateZiramamateZiramamateZiram-Cuoman2) has been studied. The results show that the single toxicity of the six compounds for Artemia is TPBPDiuronZiramCuSO_4Irgarol 1051Zn-Pt2 in the order of strength and weakness, and the results show that the toxicity of the six compounds is in the order of TPBPDiuronZiramCuSO_4Irgarol 1051Zn-Pt2. The results show that for Artemia, the single toxicity of the six compounds is TPBPDiuronZiramCuSO_4Irgarol 1051Zn-Pt2. The LC50 of Artemia for 48 h was CuSO_49.1 渭 g / cm ~ (3), Diuron 8.0 渭 g / cm ~ (3), Irgarol 1051 12.0 渭 g / cm ~ (-1) ~ (3) ~ 0 渭 g / cm ~ (3) ~ (3) ~ (?) ~ (?) TPBP 0.07 渭 g / cm ~ (3) Zn-Pt ~ (30.9) 渭 g / cm ~ (3) Ziram ~ (8.2) 渭 g / cm ~ (3). The mixed toxicity index method was used to evaluate the dualistic toxicity of Artemia (Artemia). The results showed that there were eight combinations with synergistic effects, including Irgarol 1051% Diuronon / Irgarol 1051% TPBPU Irgarol 1051% Irgarol 1051% Irgarol 1051% Zn-PtN Irgarol 1051% TPBP4 / CuSO4 and Zn-PtP / CuSO4 / CuSO4.The MTI value of the Irgarol 1051/Ziram combination was as high as 2.740Zn-PtP / CuSO4 and 5.621. It was found that five of the eight synergistic effects were related to Irgarol 1051. The results show that Irgarol 1051 has good adaptability in antifouling coating formulation based on toxicity, but Irgarol 1051 entering marine environment has the environmental risk of causing strong biological toxicity. There are also five combinations, Diuron / Zn-PtDiuron / CuSO4, TPBP / ZnPtZiram-Ziram-Ziram-PT / ZnPtZiram-Zn-Pt, showing a certain degree of antagonism. Should be used in the preparation of antifouling paint as far as possible to avoid simultaneous use.
【作者单位】：扬州大学环境科学与工程学院;扬州大学海洋科学与技术研究所;
【基金】：国家自然科学基金资助项目(41306131,41271521) 教育部科学技术研究重点资助项目(211065) 江苏省自然科学基金资助项目(BK20130440) 江苏省教育厅高校自然科学基金资助项目(13KJB180029) 扬州大学大学生科技创新资助项目
【分类号】：X171.5;X55

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