柠檬酸浓度对硼酸盐玻璃骨水泥性能的影响

发布时间：2019-05-17 10:18

【摘要】：以壳聚糖-甘油磷酸钠-柠檬酸溶液为液相,制备了一种新型可注射的硼酸盐玻璃骨水泥,通过维卡仪、万能试验机、XRD、FTIR、SEM-EDS等探究了液相中柠檬酸浓度(0.1,0.2和0.4 g/m L)对硼酸盐玻璃骨水泥性能的影响。结果表明:柠檬酸浓度显著影响骨水泥的凝结时间和可注射性。柠檬酸浓度为0.2 g/m L时获得的骨水泥的凝结时间最短,为(16±0.5)min;可注射性最好,接近100%。骨水泥压缩强度随柠檬酸浓度增大而增强,最大可达(26.7±1.9)MPa。SEM照片显示骨水泥中生成了许多纳米微粒。XRD、FTIR和EDS等结果证明,这些纳米微粒主要是硼酸盐、磷酸盐和柠檬酸盐等物质,而且柠檬酸浓度能够影响骨水泥中硼酸盐晶体的形成。此外,柠檬酸能够加速玻璃颗粒在磷酸钠盐缓冲液中的降解速率。
[Abstract]:A new injectable borate glass bone cement was prepared by using chitosan-sodium glycerophosphate-citric acid solution as liquid phase. Via Vika instrument, universal testing machine and XRD,FTIR,. SEM-EDS et al. investigated the effect of citric acid concentration (0.1, 0.2 and 0.4 g 路mL) on the properties of borate glass bone cement. The results showed that citric acid concentration significantly affected the setting time and injectability of bone cement. When the concentration of citric acid was 0.2 g / mL, the setting time of bone cement was the shortest, and the injectability of (16 卤0.5) min; was the best, which was close to 100%. The compressive strength of bone cement increases with the increase of citric acid concentration, and the maximum is (26.7 卤1.9) MPa.SEM, which shows that many nanoparticles are formed in bone cement. XRD, FTIR and EDS results show that these nanoparticles are mainly borates. Phosphate, citrate and other substances, and citric acid concentration can affect the formation of borate crystals in bone cement. In addition, citric acid can accelerate the degradation rate of glass particles in sodium phosphate buffer.
【作者单位】：同济大学材料科学与工程学院;同济大学先进土木工程材料教育部重点实验室;
【基金】：国家自然科学基金(51372170,81572105)~~
【分类号】：TQ172.1

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