水杨醛衍生物激发态下的质子转移过程及在荧光探针领域的应用

发布时间：2018-03-07 03:13

本文选题：激发态分子内质子转移　切入点：水杨醛　出处：《高等学校化学学报》2017年03期 　论文类型：期刊论文

【摘要】：从电子结构控制理论出发,通过在酚羟基对位引入吸电子取代基团稳定水杨醛中激发态的酮式构象,制备了目标化合物5-对氰基苯基-水杨醛(CN-SA).光谱测试结果显示,CN-SA表现出典型的ESIPT态荧光分子特性,而且辐射跃迁过程的酮式分配比例显著提高,荧光强度和颜色变化明显.CN-SA的荧光光谱不但能够对外围溶剂环境进行选择性识别,而且对溶解和聚集过程(聚集效应)及外围氢键形成能力的变化(pH效应和阴离子效应)等具有特异性响应,其变化可以定量表达.CN-SA仅通过结构微调即实现醇-酮构象的显著变化,可作为一个简单的多重刺激响应型荧光探针.
[Abstract]:Based on the theory of electronic structure control, the keto-type conformation of excited states in salicylic aldehyde was stabilized by introducing electron absorbent groups at p-position of phenolic hydroxyl groups. The target compound 5-p-cyanophenyl-salicylidene (CN-SAA) has been prepared. The spectral measurements show that CN-SA exhibits typical fluorescence characteristics of ESIPT state, and the ketone partition ratio in the radiative transition process is significantly increased. Fluorescence intensity and color change obviously. The fluorescence spectrum of CN-SA can not only selectively identify the peripheral solvent environment, Moreover, it has a specific response to the dissolution and aggregation process (aggregation effect) and the variation of hydrogen bond formation ability in the periphery, such as pH effect and anionic effect. The change of CN-SA can be used as a simple fluorescent probe for multiple stimuli response, which can realize the significant change of alcohol-ketone conformation only through structural fine-tuning.
【作者单位】：沈阳工业大学石油化工学院;香港科技大学深圳研究院;
【基金】：国家自然科学基金(批准号:51673118) 深圳市科技计划项目(批准号:JCYC20160428150429072)资助~~
【分类号】：O657.3

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