高性能量子点编码磁性微球的制备

发布时间：2018-03-09 06:12

本文选题：量子点　切入点：荧光　出处：《高等学校化学学报》2017年04期 　论文类型：期刊论文

【摘要】：基于改进的层层组装法,以氯仿/正丁醇混合溶液作为反应溶剂,将油溶性CdSSe/ZnS量子点装载到表面氨基修饰的磁性聚苯乙烯微球(MS)表面,通过调节量子点浓度,制备出高性能CdSSe/ZnS量子点编码磁性微球(CdSSe/ZnS-MBs).研究了氯仿和氯仿/正丁醇混合溶液对CdSSe/ZnS-MBs制备效果的影响.结果表明,氯仿/正丁醇混合溶液不仅能避免氯仿等量子点良溶剂对聚合物微球的形貌破坏,同时能促进CdSSe/ZnS量子点高效地装载到磁性微球表面.所制备的CdSSe/ZnS-MBs在水相具有较好的分散性,荧光强度变异系数(CV)小,形貌均一.该方法为简单、精确可控地制备高编码容量的量子点编码微球提供了新思路.
[Abstract]:Based on the improved layer-by-layer assembly method, the oil-soluble CdSSe/ZnS quantum dots were loaded on the surface of the magnetic polystyrene microspheres modified by the surface amino group with chloroform / n-butanol mixed solution as the reaction solvent, and the concentration of the QDs was adjusted by adjusting the concentration of the QDs. High performance CdSSe/ZnS quantum dot-coded magnetic microspheres were prepared. The effects of chloroform and chloroform / n-butanol mixed solution on the preparation of CdSSe/ZnS-MBs were studied. The mixed solution of chloroform and n-butanol can not only avoid the destruction of the morphology of polymer microspheres by the good solvent of quantum-dots such as chloroform, but also promote the CdSSe/ZnS quantum dots to be loaded onto the surface of magnetic microspheres efficiently. The prepared CdSSe/ZnS-MBs has good dispersion in aqueous phase. The fluorescence intensity coefficient of variation (CVV) is small and the morphology is uniform. This method provides a new idea for the preparation of quantum dot coded microspheres with high coding capacity.
【作者单位】：上海交通大学生物医学工程学院;
【基金】：上海交通大学医工交叉重点基金(批准号:YG2015ZD11) 国家科技支撑计划项目(批准号:2015BAI31H01)资助~~
【分类号】：O657.3

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