四苯乙烯阴离子荧光化学传感器

发布时间：2018-03-17 01:27

本文选题：四苯乙烯　切入点：化学传感器　出处：《南昌大学》2017年硕士论文　论文类型：学位论文

【摘要】：荧光化学传感器以其简单、快速、灵敏度高、选择性好等优点为当前超分子领域研究热点。近年来,以四苯乙烯衍生物为代表的具有聚集诱导发光(AIE)化合物引起人们的广泛关注。这种四苯乙烯类衍生物具有结构简单、易于合成、易于官能化、聚集状态下有较高的量子产率等特点,已被广泛应用于荧光化学传感领域。本论文合成了一系列含阴离子识别位点四苯乙烯衍生物,通过荧光发射光谱、紫外吸收光谱、1H NMR及SEM等手段详细研究了受体分子阴离子传感与识别能力,具体内容如下:1.合成了一种含咪唑基的四苯乙烯衍生物BIM-TPE。在纯水相中,BIM-TPE对焦磷酸根(PPi)具有很好的荧光增强响应,其检测线低至1.6×10-8M。通过1H NMR滴定表明BIM-TPE中双咪唑(CH)+与PPi形成了氢键作用。DLS数据显示在BIM-TPE的水溶液中分子粒度约为100 nm,当与PPi作用后,分子粒度急剧增加至1000 nm。而TEM数据显示BIM-TPE与PPi结合前后其固态形貌由~50 nm的球状聚集体变为长400-600 nm、宽约200 nm的棒状聚集体。同时,该探针成功用于生物体及水质中PPi检测。2.合成了一种含脲基四苯乙烯的有机小分子凝胶因子HGA-TPE。在EA、丙酮、乙醇等有机溶液中,HGA-TPE能够形成稳定的凝胶。同时,该凝胶对F?具有很好的应激性:随着F?加入,发生了凝胶-溶胶的转变。并通过XRD,SEM,1H NMR滴定等方法研究了其自组装及对F-的识别机理。3.以四苯乙烯为荧光团、咪唑摀(CH)+以及酰胺基NH为阴离子识别位点构建了一种咪唑荧光化学传感器HOIM-TPE。在纯水相中,详细研究了HOIM-TPE对不同阴离子及有机多磷酸盐的识别能力。结果表明:HOIM-TPE对ATP有很好的荧光增强识别能力。DLS及1HNMR滴定研究表明ATP的加入增加了受体自组装行为,导致其聚集荧光增强。
[Abstract]:The fluorescent chemical sensor is the research hotspot in the field of supramolecular in recent years because of its simplicity, rapidity, high sensitivity, good selectivity and so on. The agglomeration induced luminescence (AIEs) compounds, represented by tetrastyrene derivatives, have attracted much attention. This kind of tetrastyrene derivatives have the advantages of simple structure, easy synthesis, and easy functionalization. In this paper, a series of anion recognition site tetrastyrene derivatives have been synthesized by fluorescence emission spectra. The ability of receptor molecular anion sensing and recognition was studied in detail by UV absorption spectrum 1H NMR and SEM. The specific contents are as follows: 1. A tetrastyrene derivative BIM-TPE containing imidazolyl group has been synthesized. In pure water, BIM-TPE has a good fluorescence enhancement response to PPipyrophosphate. The detection line was as low as 1.6 脳 10 ~ (-8) M. by 1H NMR titration, it was found that diimidazolium Ch in BIM-TPE formed hydrogen bond with PPi. DLS data showed that the molecular particle size was about 100nm in the aqueous solution of BIM-TPE. The molecular particle size increased sharply to 1 000 nm. TEM data showed that the solid state morphology of BIM-TPE combined with PPi changed from 50 nm spherical aggregates to 400-600 nm long and 200 nm wide rod-shaped aggregates. The probe was successfully used for the detection of PPi in organism and water. 2. A small organic molecular gel factor HGA-TPE containing urea-tetrastyrene was synthesized. HGA-TPE can form a stable gel in organic solutions such as EAA, acetone and ethanol. Have good stress: with F? The self-assembly and recognition mechanism of F- were studied by XRDX SEM1H NMR titration. An imidazole fluorescent chemosensor HOIM-TPE was constructed with amide-NH as anion recognition site. In pure water phase, an imidazolium fluorescent chemical sensor, HOIM-TPE, was constructed. The recognition ability of HOIM-TPE to different anions and organophosphates was studied in detail. The results showed that: HOIM-TPE had a good fluorescence enhancement recognition ability to ATP. DLS and 1H NMR titration showed that the addition of ATP increased the self-assembly behavior of the receptors. Lead to its aggregation fluorescence enhancement.
【学位授予单位】：南昌大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：O657.3;TP212.2

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