艾纳香及其提取物的GC-MS指纹图谱和相关性研究

发布时间：2018-03-22 22:26

本文选题：艾纳香　切入点：艾粉　出处：《中草药》2017年04期 　论文类型：期刊论文

【摘要】：目的建立艾纳香及其提取物艾粉、艾纳香油的GC-MS指纹图谱,并进行相关性分析。方法采用GC-MS建立艾纳香、艾粉、艾纳香油指纹图谱分析方法;通过CHROMAP 1.5指纹图谱系统解决方案软件分别建立共有模式,标定共有峰,进行相似度评价,并用NIST11标准质谱库对共有指纹峰进行检索分析。结果建立了艾纳香、艾粉、艾纳香油的GC-MS指纹图谱;标定艾纳香共有峰40个、艾粉共有峰17个、艾纳香油共有峰31个,并鉴定了艾纳香40个共有指纹峰、艾粉13个共有指纹峰、艾纳香油25个共有指纹峰的化学成分;艾纳香药材相似度为0.632~0.989,提取物艾粉和艾纳香油相似度均大于0.900;艾纳香药材与其提取物指纹图谱有较好相关性。结论该方法简便、准确、可靠,可用于艾纳香、艾粉、艾纳香油的鉴别和质量控制。
[Abstract]:Objective to establish the GC-MS fingerprint of Ai Na Xiang and its extract, Artemisia powder, and Einarine oil, and to analyze their correlation. Methods GC-MS was used to establish the fingerprint analysis method of Ai Na Xiang, Ai Na powder and Ai Na sesame oil. The common pattern was established by CHROMAP 1.5 fingerprint system software, the common peak was calibrated, the similarity was evaluated, and the common fingerprint peak was searched and analyzed by NIST11 standard mass spectrometry. The GC-MS fingerprint of INA sesame oil was identified, and 40 peaks, 17 peaks and 31 peaks were identified, and the 40 peaks and 13 peaks of Artemisia powder were identified. The chemical components of 25 common fingerprint peaks of Einarine oil, the similarity degree of Herba Artemiae is 0.632n 0.989, the similarity of extract Artemisia powder and Einarine oil is greater than 0.900. There is a good correlation between Herba Sinae and its extract fingerprint. Conclusion the method is simple and accurate. Reliable, it can be used for the identification and quality control of Ainaram, Artemisia powder and Ena sesame oil.
【作者单位】：贵州省药物制剂重点实验室;贵州医科大学药学院;民族药与中药开发应用教育部工程研究中心/国家苗药工程技术研究中心;
【基金】：贵州省科技成果转化项目(20155201) 贵州省联合基金项目(20157356) 贵州省中药现代化专项项目(20134001) 贵州省优青项目(201511) 贵州省教育厅项目(201304,ZYRC2014012) 贵州省创新人才团队项目(20165613)
【分类号】：R284;O657.63

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