钯纳米粒子修饰的三甲氧苄啶分子印迹膜传感器的制备及其识别性能研究

发布时间：2018-03-26 12:30

本文选题：钯纳米粒子　切入点：三甲氧苄啶　出处：《分析化学》2017年09期

【摘要】：采用N,N'-亚甲基双丙烯酰胺(MBA)为功能单体、钯纳米粒子为掺杂剂、马来松香丙烯酸乙二醇酯为交联剂,在玻碳电极上热聚合具有三甲氧苄啶(TMP)识别性能的钯纳米材料修饰的分子印迹传感膜。采用扫描电镜及红外光谱对合成的钯纳米材料、印迹传感膜的形貌及其结构进行了表征;采用循环伏安法(CV)、交流阻抗法(EIS)对钯纳米粒子掺杂的印迹电极与无掺杂电极的电化学性能进行了研究。结果表明,纳米粒子掺杂的印迹电极与无掺杂电极的表面形貌及电化学性能明显不同。差分脉冲伏安法(DPV)表征结果表明,TMP的浓度在5.0×10~(-7)~4.0×10~(-3)mol/L范围内与脉冲峰电流呈良好的线性关系(R=0.9995),检出限为3.2×10~(-8)mol/L(S/N=3)。此钯纳米粒子掺杂的印迹传感器具有较高的灵敏度。即时电流测定结果表明,新诺明(SMZ)、磺胺嘧啶(SDZ)、葡萄糖(Glu)、尿素(Urea)对三甲氧苄啶(TMP)的测定不产生干扰。将此印迹传感器用于实际样品中TMP的检测,加标回收率为96.8%~102.0%。
[Abstract]:In this paper, the functional monomers, palladium nanoparticles and maleic rosin acrylic acid glycol ester were used as functional monomer and crosslinking agent respectively. The molecular imprinted sensing films modified by palladium nanomaterials with trimethoprim (TMP) recognition properties were synthesized by thermal polymerization on glassy carbon electrode. The morphology and structure of the imprinted films were characterized by scanning electron microscopy and infrared spectroscopy. The electrochemical properties of imprinted and non-doped palladium nanoparticles electrode were studied by cyclic voltammetry and electrochemical impedance spectroscopy (EIS). The surface morphology and electrochemical properties of the imprinted electrode doped with nano-particles are obviously different from those of the non-doped electrode. The results of differential pulse voltammetry (DPV) show that there is a good linear relationship between the concentration of TMP and the peak current of the pulse in the range of 5.0 脳 10 ~ (-1) ~ (-7) 脳 10~(-3)mol/L. The detection limit is 3.2 脳 10 ~ (-1) ~ (-8) mol / L ~ (-1) S / N ~ (3 +). The imprinted sensor doped with palladium nanoparticles has high sensitivity. The determination of trimethoprim (TMP) was not interfered with by SMC, SDZN, Glun, Urea. The imprinted sensor was applied to the determination of TMP in actual samples. The recovery rate of the imprinting sensor was 96.80.102.0%.
【作者单位】：广西民族大学化学化工学院广西林产化学与工程重点实验室;广西民族大学化学化工学院广西多糖材料与改性重点实验室;广西民族大学化学化工学院广西高校食品安全与药物分析化学重点实验室;
【基金】：广西自然科学基金(No.2015GXNSFAA139040) 广西中青年教师基础能力提升项目(No.2017KY0171) 广西民族大学校级科研项目(No.2016MDYB023)资助
【分类号】：O631.3

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