水杨醛缩卡巴肼烃基锡配合物的合成、结构及除草活性研究

发布时间：2018-05-02 04:39

本文选题：水杨醛缩卡巴肼 + 烃基锡配合物　；参考：《湘潭大学》2017年硕士论文

【摘要】：卡巴肼及其衍生物具有较强的生物活性,既是合成药物的重要中间体,也是一种含O、N和S的良好配体,通过其氨基与芳醛缩合形成双(取代水杨醛)缩卡巴肼,具有多个配位点,可与有机锡配位,组装成Sn-O(N,S)键的有机锡配合物。本论文合成了双(取代水杨醛)缩卡巴肼化合物,再将其与烃基锡前体反应,合成双(取代水杨醛)缩卡巴肼烃基锡配合物。经元素分析和谱学表征,并用X-射线单晶衍射方法测定典型新配合物的晶体分子结构,初步测试了双(取代水杨醛)缩卡巴肼配体化合物及其相应烃基锡配合物的生物除草活性。主要研究内容如下:一、在中性或弱碱性环境中,卡巴肼或硫代卡巴肼与取代水杨醛缩合,合成了11个双(取代水杨醛)缩卡巴肼配体,其中8个双(取代水杨醛)缩卡巴肼配体为未见文献报道的化合物。二、以二丁基氧化锡、二苄基二氯化锡和单丁基三氯化锡等烃基锡为原料,与双(取代水杨醛)缩卡巴肼配体反应,合成了19个双(取代水杨醛)缩卡巴肼烃基锡配合物,其中17个为未见文献报道的化合物。三、对双(取代水杨醛)缩卡巴肼配体和双(取代水杨醛)缩卡巴肼烃基锡配合物进行元素分析、IR、~1H NMR、~(13)C NMR表征,并通过培养晶体,用X-射线单晶衍射方法,研究了10个新双(取代水杨醛)缩卡巴肼烃基锡配合物的晶体分子结构。四、采用平皿法,分别测定了11个双(取代水杨醛)缩卡巴肼配体和19个双(取代水杨醛)缩卡巴肼烃基锡配合物对马齿苋、刺苋、决明子等杂草及农作物四九菜心、苋菜等植株的生物除草活性,除草活性表明:在测试浓度范围内,大部分的配合物对测试的杂草都有良好的抑制生长作用。且有少部分配合物在对杂草有良好抑制作用的同时不影响两种农作物的生长,具有优良的选择性。
[Abstract]:Carbazide and its derivatives have strong biological activity, which is not only an important intermediate of synthetic drugs, but also a good ligand containing O _ (N) and S, which condensates with aromatic aldehydes to form bis (substituted salicylic) carbazide by condensation of its amino groups with aromatic aldehydes. Organotin complexes with multiple coordination sites can be assembled with organotin bonds. In this paper, bis (substituted salicylic aldehyde) carbazide compound was synthesized and reacted with alkyltin precursor to synthesize bis (substituted salicylaldehyde) carbazide alkyl tin complex. The crystal and molecular structures of typical new complexes were characterized by elemental analysis and spectroscopic analysis. The bioherbicidal activity of bis (substituted salicylaldehyde) carbazide ligands and their corresponding alkyl tin complexes were preliminarily tested. The main contents are as follows: 1. In neutral or weak alkaline environment, 11 bis (substituted salicylic) carbazid ligands were synthesized by condensation of carbazide or thiocarbazid with substituted salicylic aldehyde. Eight bis (substituted salicylic aldehydes) carbazide ligands are unreported compounds. Second, 19 alkyltin bis (substituted salicylaldehyde) carbazide alkyltin complexes were synthesized by the reaction of alkyl tin with bis (substituted salicylaldehyde), dibenzyltin dichloride and tributyltin trichloride with bis (substituted salicylic aldehyde) carbazide ligand. Among them, 17 compounds were not reported in the literature. Third, the ligands of bis (substituted salicylaldehyde) carbazide and bis (substituted salicylaldehyde) carbazide alkyl tin complexes were characterized by elemental analysis, 1H NMRN ~ (13) C NMR. The crystal and molecular structure of 10 new bis (substituted salicylaldehyde) carbazide alkyl tin complexes were studied. 4. Eleven bis (substituted salicylic aldehyde) carbazide ligands and 19 bis (substituted salicylic aldehyde) carbazide alkyltin complexes for Portulaca oleracea, purslane, cassia seed and their crops were determined by plate method. The bioherbicidal activity and herbicidal activity of amaranth and other plants showed that most of the complexes had a good inhibitory effect on weeds in the range of test concentration. A few of the complexes had good inhibition on weeds and did not affect the growth of two crops, so they had excellent selectivity.
【学位授予单位】：湘潭大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：O641.4;TQ457.2

【参考文献】