配体促进下铜催化的由醛制备过酸叔丁酯及烯丙酯的反应研究

发布时间：2018-05-02 21:57

  本文选题：铜催化 + 氮配体　； 参考：《有机化学》2017年05期

【摘要】：以碘化亚铜为催化剂、2,2'-联吡啶为配体,发展了一种高效、温和且无溶剂参与的催化醛的C—H键活化、与过氧化叔丁醇(TBHP)反应生成过酸酯化合物的反应体系.在该催化体系中,双齿氮配体的加入显著增强了Cu(I)催化剂的催化活性,对该反应起到了关键的开关作用.与文献报道相比,该反应体系反应条件温和、时间短、无需溶剂且底物适应性优良.在此基础上,以上述反应混合物直接与环己烯反应,在较低温度下成功实现了烯丙酯的"一锅法"串联合成.
[Abstract]:Using cuprous iodide as catalyst, cuprous iodide as ligand, a high efficient, mild and solvent free catalyst for the activation of C-H bonds of aldehydes was developed, which reacted with tert butanol peroxide (TBHP) to form superacid esters. In this system, the addition of didentate nitrogen ligands significantly enhanced the catalytic activity of the catalyst, which played a key role in the reaction. Compared with the literature, the reaction conditions are mild, the reaction time is short, the solvent is not needed and the substrate has good adaptability. On this basis, the "one pot" series synthesis of allyl ester was successfully realized at lower temperature by the reaction of cyclohexene directly with the above reaction mixture.
【作者单位】： 南京航空航天大学材料科学与技术学院应用化学系;
【基金】：国家自然科学基金(Nos.21472092,21172107) 江苏高校优势学科建设工程资助项目~~
【分类号】：O623.624
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本文编号：1835655