基于原位合成量子点的铜离子荧光传感器

发布时间：2018-05-08 03:22

本文选题：铜离子 + 荧光传感器　；参考：《分析试验室》2017年03期

【摘要】：建立基于半胱氨酸调控量子点合成的新型荧光传感器用于Cu~(2+)的快速、灵敏检测。以半胱氨酸为稳定剂,可在室温条件快速原位合成水溶性的荧光量子点。通过Cu~(2+)催化半胱氨酸氧化而抑制量子点的生长。由于催化形成的胱氨酸产物失去有效的稳定作用,导致合成的量子点数量减少,从而实现Cu~(2+)的荧光检测。在5~400 nmol/L范围内,Cu~(2+)浓度与荧光信号呈良好的线性关系,检出限为4.2 nmol/L。该传感器对Cu~(2+)具有良好选择性。用于闽江水中Cu~(2+)的测定,结果与ICP-MS方法接近。所建立的传感器具有操作简便、成本低及快速等优点。整个传感过程在15 min内即可完成。因此,在其它多种目标分析物的间接检测中具有广泛的应用前景。
[Abstract]:A novel fluorescence sensor based on cysteine controlled quantum dot synthesis was developed for Cu~(2. Using cysteine as stabilizer, water-soluble fluorescent quantum dots can be rapidly synthesized in situ at room temperature. The growth of quantum dots was inhibited by the oxidation of cysteine catalyzed by Cu~(2. Due to the loss of the effective stability of the cystine product, the number of synthesized QDs is reduced, and the fluorescence detection of Cu~(2) is realized. There is a good linear relationship between the concentration of Cu ~ (2) and the fluorescence signal in the range of 5 ~ 400 nmol/L, and the detection limit is 4.2 nmol / L ~ (-1). The sensor has good selectivity to Cu~(2. The method was applied to the determination of Cu~(2 in Minjiang River water. The result is close to that of ICP-MS method. The sensor has the advantages of simple operation, low cost and high speed. The whole sensing process can be completed within 15 min. Therefore, it has a wide application prospect in indirect detection of other target analytes.
【作者单位】：福建农林大学食品科学学院;福建医科大学药学院;
【基金】：国家自然科学基金项目(21605019) 福建省自然科学基金项目(2015J01083,2016J01049) 福建省中青年教师教育科研项目(JA15201) 福建农林大学高水平大学建设项目(612014042)资助
【分类号】：O657.3

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