基于纳米金Core-satellites等离子体耦合增强效应的汞离子光纤传感器的研究

发布时间：2018-05-13 17:32

本文选题：局域等离子体共振 + 纳米金Core-satellites结构　；参考：《分析化学》2017年06期

【摘要】：以DNA杂交双链为联接,构建纳米金颗粒Core-satellites结构并激发等离子体耦合增强效应,利用Hg~(2+)可与DNA中胸腺嘧啶T形成T-Hg~(2+)-T特异性结构,研制了用于检测水中Hg~(2+)的局域等离子体共振(LSPR)光纤传感器。待测溶液中的Hg~(2+)能够引起富含T的DNA单链折叠,抑制DNA杂交反应,降低等离子体耦合强度,改变LSPR谐振波长。通过检测谐振波长红移变化,实现对Hg~(2+)浓度的定量检测。本方法检测Hg~(2+)的线性范围为5~150 nmol/L,检出限为3.4 nmol/L(3σ)。Zn~(2+)、Mg~(2+)、Pb~(2+)等重金属离子对Hg~(2+)检测无明显干扰作用。实际水样中Hg~(2+)加样回收率为94.2%~105.4%,相对标准偏差4.8%。
[Abstract]:Core-satellites structure of gold nanoparticles was constructed by using DNA hybridization double strand as a link, and plasma coupling enhancement effect was stimulated. Using Hg~(2), the T-Hg~(2 ~ + -T specific structure was formed with thymidine T in DNA. A local plasmon resonance (LSR) optical fiber sensor for detecting Hg~(2 in water has been developed. The Hg~(2 in the solution under test can induce T rich DNA single strand folding, inhibit the DNA hybridization reaction, decrease the plasma coupling intensity and change the LSPR resonant wavelength. The quantitative detection of Hg~(2 concentration is realized by detecting the red shift of resonant wavelength. The linear range for the detection of Hg~(2 is 5 ~ 150nmol / L, and the detection limit is 3.4 nmol/L(3 蟽 ~ (1). The detection limit is 3.4 nmol/L(3 蟽 ~ (2 +). There is no obvious interference to the detection of Hg~(2 by heavy metal ions. The recoveries of Hg~(2 in actual water samples were 94.2% and 105.4% respectively, and the relative standard deviation (RSDs) was 4.8%.
【作者单位】：中国科学院电子学研究所传感技术国家重点实验室;中国科学院大学;东北大学秦皇岛分校;
【基金】：国家重点基础研究发展计划(No.2015CB352100) 国家自然科学基金(No.61501100) 秦皇岛市科技支撑计划(No.2012021A100)资助项目~~
【分类号】：O657.3;TP212

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