3-异硫氰酸酯氧化吲哚参与的不对称串联反应研究进展
发布时间:2019-01-26 08:06
【摘要】:3-异硫氰酸酯氧化吲哚是一类高活性的新型反应试剂,已经被广泛地应用于串联反应中,并用于结构多样的手性螺环氧化吲哚骨架的构建.简单综述了近六年来3-异硫氰酸酯氧化吲哚参与的几类串联环化反应的最新研究进展,主要介绍各反应的特点、活化模式及合成应用,并展望它的发展前景.
[Abstract]:3-isothiocyanate oxyindole is a new kind of reagents with high activity. It has been widely used in series reaction and in the construction of chiral spiro-epoxide indole skeleton with various structures. The recent progress in several series cyclization reactions involving 3-isothiocyanate oxyindoles in the past six years is briefly reviewed. The characteristics, activation modes and synthesis applications of each reaction are mainly introduced, and its development prospect is also prospected.
【作者单位】: 湖北第二师范学院植物抗癌活性物质提纯与应用湖北省重点实验室;华中师范大学化学学院农药与化学生物学教育部重点实验室;
【基金】:国家自然科学基金(No.21602052) 湖北省教育厅科学技术研究(No.Q20163004)资助项目~~
【分类号】:O621.25
本文编号:2415287
[Abstract]:3-isothiocyanate oxyindole is a new kind of reagents with high activity. It has been widely used in series reaction and in the construction of chiral spiro-epoxide indole skeleton with various structures. The recent progress in several series cyclization reactions involving 3-isothiocyanate oxyindoles in the past six years is briefly reviewed. The characteristics, activation modes and synthesis applications of each reaction are mainly introduced, and its development prospect is also prospected.
【作者单位】: 湖北第二师范学院植物抗癌活性物质提纯与应用湖北省重点实验室;华中师范大学化学学院农药与化学生物学教育部重点实验室;
【基金】:国家自然科学基金(No.21602052) 湖北省教育厅科学技术研究(No.Q20163004)资助项目~~
【分类号】:O621.25
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