无需自由基引发剂参与实现可见光诱导Barton脱羧（英文）
发布时间：2021-12-17 14:54
报道了一种可见光诱导Barton脱羧的新方法.在不需要外加自由基引发剂的条件下,可以实现一系列一级、二级、三级以及氨基酸、多肽类氧化还原性羧酸酯脱羧,而且许多含有羧基的天然产物及药物分子也可以很好地发生转化,反应条件温和、底物范围广,具有良好的收率和官能团兼容性.初步机理实验研究表明,三（三甲基硅基）硅烷在该反应体系中不仅作为氢源,同时也作为电子给体和氧化还原性羧酸作用形成电子供体-受体复合物,反应经历自由基历程.
【文章来源】：中国科学技术大学学报. 2020,50(11)北大核心CSCD
【文章页数】：8 页
【文章目录】：
1 Introduction
2 Results and discussion
2.1 Screening of reaction conditions
2.2 Scope of the decarboxylation
2.3 Mechanistic investigation
3 Conclusions
4 Experimental section
4.1 General procedure
4.2 Characterization data for products
Conflict of interest
【参考文献】：
期刊论文
[1]Transition metal-catalyzed decarboxylative cross-coupling reactions[J]. SHANG Rui~1 & LIU Lei~1,2*1Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education); Department of Chemistry, Tsinghua University, Beijing 100084, China 2State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032,China. Science China（Chemistry）. 2011(11)
本文编号：3540355
【文章来源】：中国科学技术大学学报. 2020,50(11)北大核心CSCD
【文章页数】：8 页
【文章目录】：
1 Introduction
2 Results and discussion
2.1 Screening of reaction conditions
2.2 Scope of the decarboxylation
2.3 Mechanistic investigation
3 Conclusions
4 Experimental section
4.1 General procedure
4.2 Characterization data for products
Conflict of interest
【参考文献】：
期刊论文
[1]Transition metal-catalyzed decarboxylative cross-coupling reactions[J]. SHANG Rui~1 & LIU Lei~1,2*1Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education); Department of Chemistry, Tsinghua University, Beijing 100084, China 2State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032,China. Science China（Chemistry）. 2011(11)
本文编号：3540355
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