纳米针状表面改性的仿生多孔钛植入体及体外成骨性能（英文）

发布时间：2018-03-02 09:13

本文关键词： 纳米针状表面改性仿生多孔钛成骨性能冷冻铸造热氧化法　出处：《Transactions of Nonferrous Metals Society of China》2017年08期 　论文类型：期刊论文

【摘要】：通过冷冻铸造和热氧化法制备一种新型兼具抗菌功能和良好骨整合性能的纳米针状表面改性仿生多孔钛植入体。分析和表征仿生多孔钛植入体的孔隙形貌和尺寸、力学性能和体外成骨性能。结果表明:当控制冷冻铸造工艺中浆料中钛粉体积比为10%时,多孔试样的孔隙度为(58.32±1.08)%、孔径为(126.17±18.64)μm、压缩强度为(58.51±20.38)MPa、弹性模量为(1.70±0.52)GPa。在1200°C烧结1 h,多孔试样的孔隙度为(58.24±1.50)%、孔径为(124.16±13.64)μm、压缩强度为(54.77±27.55)MPa、弹性模量为(1.63±0.30)GPa。通过热氧化方法在多孔钛植入体试样的孔隙表面制备出均匀分布的纳米针状结构。通过对工艺的优化,制备出具有良好孔隙形貌和尺寸,同时具备良好力学性能和体外成骨性能的纳米针状表面改性仿生多孔钛植入体,具有重要的临床应用前景。
[Abstract]:A novel nano-needle surface modified biomimetic porous titanium implant was prepared by freezing casting and thermal oxidation. The pore morphology and size of the biomimetic porous titanium implant were analyzed and characterized. Mechanical properties and osteogenic properties in vitro. The results show that when the volume ratio of titanium powder in the slurry is 10, when the volume ratio of titanium powder in the slurry is 10, The porosity of porous specimen was 58.32 卤1.08m, pore diameter was 126.17 卤18.64 渭 m, compressive strength was 58.51 卤20.38mPa, elastic modulus was 1.70 卤0.52GPa.The porosity of porous specimen was 58.24 卤1.50 渭 m, pore diameter was 124.16 卤13.64 渭 m, compressive strength was 54.77 卤27.55MPa, elastic modulus was 1.63 卤0.30GPa. by thermal oxidation method, porosity of porous specimen was 58.24 卤1.50 渭 m, pore diameter was 124.16 卤13.64 渭 m, compressive strength was 54.77 卤27.55 MPA, elastic modulus was 1.63 卤0.30GPa. the porosity of porous specimen was 58.24 卤1.50 渭 m, pore diameter was 124.16 卤13.64 渭 m, compressive strength was 54.77 卤27.55 MPA, elastic modulus was 1.63 卤0.30GPa. A uniform distribution of nano-needle structure was prepared on the pore surface of the sample. The biomimetic porous titanium implants with good pore morphology and size, good mechanical properties and osteogenic properties in vitro were prepared, which have important clinical application prospects.
【作者单位】：中南大学湘雅三医院;中南大学粉末冶金国家重点实验室;
【基金】：Projects(51290295,51305464) supported by the National Natural Science Foundation of China Project(2016JJ6156) supported by the Natural Science Foundation of Hunan Province,China Project(2016JC2064) supported by the Key Research and Development Program of Hunan Province,China Project(20130162120094) supported by the Specialized Research Fund for the Doctoral Program of Higher Education,China
【分类号】：R318.08;TG292

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