PAMPS-PAAM互穿网络凝胶的摩擦磨损性能研究

发布时间：2018-04-20 14:56

本文选题：人工软骨 + PAMPS-PAAM凝胶　；参考：《北京化工大学》2012年硕士论文

【摘要】：关节软骨是人体的重要器官，依靠天然软骨优异的摩擦磨损性能和抗压减震性能，人们得以在生活中进行各种高强度的工作和运动。在当前的关节假体置换手术中，关节软骨的作用已经越来越受到重视。水凝胶的结构和性能与天然软骨相似，并具有良好的生物相容性，，因此被认为是替代天然软骨的新材料。本文选用2－丙烯酰胺－2－甲基丙磺酸（AMPS）凝胶和丙烯酰胺（AAM）溶液制备PAMPS-PAAM互穿网络凝胶，开展了以下研究工作： 1、考察了PAMPS-PAAM凝胶的力学性能：其蠕变特性和压缩强度接近天然软骨。 2、在自制销-盘式摩擦实验机上进行PAMPS-PAAM互穿网络凝胶的摩擦性能实验，比较全面地考察了不同摩擦学条件下PAMPS-PAAM凝胶的摩擦性能：在0.7MPa、25%小牛血清润滑、 PAMPS-PAAM/PAMPS-PAAM摩擦副的条件能获得最优的摩擦磨损性能。 3、通过研究PAMPS-PAAM凝胶的Stribeck曲线，讨论了其润滑机理。 4、比较了PAMPS-PAAM凝胶与常用的人工软骨材料——UHMWPE在相同摩擦条件下的摩擦学性能：在理想的摩擦学条件下，PAMPS-PAAM凝胶的摩擦学性能优于UHMWPE，但其摩擦学性能随摩擦条件的变化而改变较大，UHMWPE在各种摩擦条件下的摩擦学性能都比较稳定。
[Abstract]:Articular cartilage is an important organ of human body. Depending on the excellent friction and wear performance of natural cartilage and its anti-shock resistance, people can work and exercise with high intensity in their daily life. The role of articular cartilage has been paid more and more attention in the current arthroplasty. The structure and properties of hydrogels are similar to those of natural cartilage and have good biocompatibility, so hydrogels are considered as a new substitute for natural cartilage. In this paper, PAMPS-PAAM interpenetrating network gels were prepared by using 2-acrylamide-2-methylpropanesulfonic acid (AMP) gel and acrylamide AAM) solution. The following research work was carried out: 1. The mechanical properties of PAMPS-PAAM gel were investigated. The creep properties and compressive strength of PAMPS-PAAM gel were close to those of natural cartilage. 2. The friction properties of PAMPS-PAAM interpenetrating network gels were tested on a self-made pin-disc friction tester. The tribological properties of PAMPS-PAAM gels under different tribological conditions were investigated. The optimum friction and wear properties of PAMPS-PAAM/PAMPS-PAAM pairs were obtained under the conditions of 25% calf serum lubrication at 0.7 MPA. 3. The lubrication mechanism of PAMPS-PAAM gel was discussed by studying its Stribeck curve. 4. The tribological properties of PAMPS-PAAM gel and common artificial cartilage material UHMWPE under the same friction conditions were compared. The tribological properties of PAMPS-PAAM gel under ideal tribological conditions were better than those of UHMWPE gel, but the tribological properties of UHMWPE gel with friction conditions were higher than those of UHMWPE gel. The tribological properties of UHMWPE are stable under various friction conditions.
【学位授予单位】：北京化工大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：TH117.1

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