噬菌体控制植物细菌性疾病的研究进展

发布时间：2018-04-10 09:39

  本文选题：噬菌体　切入点：植物细菌性疾病　出处：《中国抗生素杂志》2017年09期

【摘要】：尽管植物的病原菌大多数为真菌,但细菌也是引起农业经济损失的主要原因之一。由于缺乏有效的杀菌剂,且细菌产生了耐药性,植物细菌性疾病的爆发通常是难以控制的。目前,噬菌体具有替代传统化学农药的潜力,使用噬菌体防治植物细菌性疾病正处于一个快速发展的阶段,商业化的噬菌体产品已被用于植物疾病的防治。在农业中,限制噬菌体使用的主要因素是环境影响和抗性宿主菌的产生。为降低环境因素对噬菌体的干扰,可使用保护剂、避免阳光直射以及使用无毒或减毒的菌株等方法来解决。同时,可使用噬菌体鸡尾酒(噬菌体混合液)进行细菌抗性管理。在未来,噬菌体治疗会作为植物疾病控制综合管理的一部分,并具有广阔的发展前景。
[Abstract]:Although plant pathogens are mostly fungi, bacteria are also one of the main causes of agricultural economic losses.The outbreak of plant bacterial diseases is often difficult to control due to the lack of effective fungicides and bacterial resistance.At present, bacteriophages have the potential to replace traditional chemical pesticides. The use of bacteriophages to control plant bacterial diseases is in a rapid development stage, commercial phage products have been used to prevent and cure plant diseases.In agriculture, the main factors limiting the use of phages are the environmental effects and the production of resistant host bacteria.In order to reduce the interference of environmental factors to bacteriophage, protective agents, direct sunlight and non-toxic or attenuated strains can be used to solve the problem.At the same time, bacteriophage cocktail (bacteriophage mixture) can be used for bacterial resistance management.In the future, bacteriophage therapy will be a part of plant disease control integrated management, and has a broad development prospects.
【作者单位】： 大连理工大学生命科学与技术学院;动物性食品安全保障技术教育部工程研究中心;大连赛姆生物工程技术公司;
【基金】：国家海洋公益项目(No.201405003-3)
【分类号】：S432.42
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本文编号：1730670