动脉瘤性蛛网膜下腔出血（aSAH）临床数据库软件研发

发布时间：2018-06-19 13:46

本文选题：数据库 + aSAH　；参考：《福建医科大学》2016年硕士论文

【摘要】：目的:动脉瘤性蛛网膜下腔出血是临床上常见的急性脑血管疾病,其年发生率达6~35.3/10万,是仅次于脑血栓和高血压脑出血的脑血管疾病,具有高致死率和致残率。目前在研究其临床特点、影响因素、干预因素、流行病学和预后等相关领域时产生了大量的临床数据,这些大数据需要整合、归纳和分析,并且需要一个较为完整的数据库来录入、整合和提取所需的数据。从当前医疗行业领域信息化水平的特点来看,任何医学科技创新与医疗技术发展都离不开临床数据的支持,临床数据库的建立显得尤为重要,因此需要建立一个智能化的动脉瘤性蛛网膜下腔出血(a SAH)临床数据库,为临床与科研提供数据平台。方法:结合我国a SAH的诊疗现状和未来需求,参考国外临床数据库建设的经验和理论并结合a SAH临床指南及相关指南,制定科学、合理的a SAH数据库内容及结构。以a SAH的临床诊疗数据作为目标数据,设计数据的采集和存储方式,建立基于WEB的电子数据库录入、检索与统计的医疗专业软件系统,为临床诊疗和科研提供数据检索与计算平台。采用基于B/S的三层设计模式,利用ASP.NET和SQL数据库相结合技术,实现数据的互联网共享。通过与医院现有的医疗管理软件对接,自动导入临床数据,实现数据的自动采集、整理、导出和联网共享,并应用该临床数据库进行a SAH相关的临床诊疗和科研。结果:研制了能够较为全面反映整个a SAH患者临床诊疗过程的数据库内容和结构,包括个人基本资料、入院时情况、a SAH出血特点、夹闭手术及介入栓塞、围手术期处理、出院及随访七个部分,包含了1000多个字段和它们的层次关系结构设计。研制了基于数据库内容结构,以浏览器/服务器为数据登录方式,具备安全性验证、数据管理、录入和导出、联网共享以及统计分析等功能的数据库管理系统。该数据库录入界面友好,能够与医院的医疗管理软件对接,同时数据可以存储在各种设备上,从数据中心最大的服务器一直到桌面计算机和移动设备,它都可以控制数据而不受存储的位置限制。通过对数据库的应用分析,验证了本数据库具备全面、高效的数据资料收集能力,以及对数据进行科学、有效管理和分析的功能,并对所面临的困难与问题做进一步地调整。结论:数据库的研发使我们摆脱以往临床研究时以翻查纸质病历资料为主的传统模式,将a SAH临床资料和数据信息有序存储,统一管理,并设计创新的检索和计算模块,方便、高效地获取目标临床数据及进行相应统计分析,同时借助互联网为临床科研提供随时随地可供调阅的数据平台。因此建立一个适合于我国a SAH诊治现状和发展要求的数据库是可行的,所建立的该数据库可适用于临床,能够基本满足a SAH临床诊疗和科学研究的需要。
[Abstract]:Objective: aneurysm subarachnoid hemorrhage (SAH) is a common acute cerebrovascular disease with an annual incidence of 635. 3 / 10 million. It is second only to cerebral thrombosis and hypertensive intracerebral hemorrhage and has a high mortality and disability rate. At present, a large number of clinical data have been produced in the study of clinical characteristics, influencing factors, intervention factors, epidemiology and prognosis. These big data need to be integrated, summarized and analyzed. And need a more complete database to input, integrate and extract the required data. From the characteristics of the current level of information in the medical field, any medical science and technology innovation and medical technology development can not be separated from the support of clinical data, the establishment of clinical database is particularly important. Therefore, it is necessary to establish an intelligent clinical database of aneurysm subarachnoid hemorrhage (SAH) to provide a data platform for clinical and scientific research. Methods: according to the current situation and future demand of diagnosis and treatment of aSAH in our country, referring to the experience and theory of clinical database construction in foreign countries, and combining with the clinical guidelines and related guidelines of aSAH, the scientific and reasonable content and structure of aSAH database were worked out. Taking the clinical diagnosis and treatment data of aSAH as the target data, the collection and storage of the data are designed, and the medical professional software system is established based on the electronic database input, retrieval and statistics. To provide a data retrieval and computing platform for clinical diagnosis and research. Using the three-tier design pattern based on B / S and the technology of ASP. Net and SQL database, the data sharing on the Internet is realized. Through docking with the existing medical management software of the hospital, the clinical data are automatically imported, the data are automatically collected, sorted, exported and shared online, and the clinical database is used for clinical diagnosis and scientific research related to the aSAH. Results: the contents and structure of the database which can reflect the whole clinical diagnosis and treatment process of patients with aSAH were developed, including the basic personal data, the characteristics of SAH bleeding at admission, clipping operation and interventional embolization, and perioperative management. Discharge and follow-up seven parts, including more than 1000 fields and their hierarchical structure design. A database management system based on database content structure is developed, which uses browser / server as data login mode and has the functions of security verification, data management, input and export, network sharing and statistical analysis. The database has a friendly interface, docking with hospital medical management software, and data can be stored on a variety of devices, from the largest server in the data center to desktop computers and mobile devices. It can control the data without being restricted by the location of the storage. Through the application and analysis of the database, it is verified that the database has the capability of comprehensive and efficient data collection, as well as the function of scientific, effective management and analysis of the data, and further adjustment is made to the difficulties and problems encountered. Conclusion: the research and development of the database make us get rid of the traditional mode of looking up the paper medical records in the past clinical research, store the clinical data and data information of aSAH in an orderly way, manage the data uniformly, and design the innovative retrieval and calculation module, which is convenient. The target clinical data can be obtained and analyzed efficiently, and the data platform can be accessed anytime and anywhere with the help of the Internet. Therefore, it is feasible to establish a database suitable for the status quo and development requirements of the diagnosis and treatment of aSAH in China. The database can be applied to clinical practice and can basically meet the needs of clinical diagnosis and treatment and scientific research of aSAH.
【学位授予单位】：福建医科大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：TP311.52;R743.35

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