动脉瘤性蛛网膜下腔出血后迟发性脑缺血的危险因素研究进展

发布时间：2018-05-04 07:38

本文选题：动脉瘤 + 蛛网膜下腔出血　；参考：《河北医科大学》2017年硕士论文

【摘要】：为了调查清楚动脉瘤性蛛网膜下腔出血后迟发性脑缺血危险因素。迟发性脑缺血是动脉瘤性蛛网膜下腔出血的最重的并发症之一。了解其危险因素对于它的预防和治疗有着非常重要的意义。使用标准搜索引擎,包括PubMed,关于动脉瘤性蛛网膜下腔出血后迟发性脑缺血的医学文献进行了回顾。CT扫描显示重度蛛网膜下腔出血是唯一一致的动脉瘤性蛛网膜下腔出血后迟发性脑缺血的危险因素.迟发性脑缺血相关危险因素包括:年龄、临床分级、再出血、脑室内或脑内出血、急性脑积水、动脉瘤大小、部位、白细胞增多、白细胞介素-6水平和心脏畸形,这些似乎与蛛网膜下腔出血的严重程度相关而不是每一个因素都有直接影响。吸烟、高血压、心电图示左室肥厚与迟发性脑缺血有关,但是和蛛网膜下腔出血的严重程度无关。重度的蛛网膜下腔出血是一个最为明确的动脉瘤性蛛网膜下腔出血后迟发性脑缺血的危险因素,其次是吸烟,高血压,左室肥厚。但是迟发性脑缺血的发病机制,目前尚不明确,为了进一步了解迟发性脑缺血的发病机制,进一步研究,尤其是与动脉瘤性蛛网膜下腔出血严重程度无关的危险因素的研究是必要的。
[Abstract]:To investigate the risk factors of delayed cerebral ischemia after aneurysm subarachnoid hemorrhage. Delayed cerebral ischemia is one of the most serious complications of aneurysm subarachnoid hemorrhage. Understanding its risk factors is of great significance for its prevention and treatment. Using standard search engines, A review of the medical literature on delayed cerebral ischemia after aneurysm subarachnoid hemorrhage. Ct scans showed that severe subarachnoid hemorrhage was the only consistent risk factor for delayed cerebral ischemia after aneurysm subarachnoid hemorrhage. Risk factors associated with delayed cerebral ischemia included age, clinical grade, rebleeding, intraventricular or intracerebral hemorrhage, acute hydrocephalus, aneurysm size, location, leukopenia, interleukin-6 level, and cardiac malformation. These seem to be directly related to the severity of subarachnoid hemorrhage rather than to each factor. Smoking, hypertension and electrocardiogram showed that left ventricular hypertrophy was associated with delayed cerebral ischemia, but not with the severity of subarachnoid hemorrhage. Severe subarachnoid hemorrhage is the most definite risk factor for delayed cerebral ischemia after aneurysm subarachnoid hemorrhage followed by smoking hypertension and left ventricular hypertrophy. However, the pathogenesis of delayed cerebral ischemia is still unclear. In order to further understand the pathogenesis of delayed cerebral ischemia, In particular, the study of risk factors unrelated to the severity of aneurysm subarachnoid hemorrhage is necessary.
【学位授予单位】：河北医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R743.35

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